Ecology and functional potential of phyllosphere yeasts

L Gouka, JM Raaijmakers, V Cordovez - Trends in Plant Science, 2022 - cell.com
The phyllosphere (ie, the aerial parts of plants) harbors a rich microbial life, including
bacteria, fungi, viruses, and yeasts. Current knowledge of yeasts stems primarily from …

Evolutionary rescue of phosphomannomutase deficiency in yeast models of human disease

RC Vignogna, M Allocca, M Monticelli, JW Norris… - Elife, 2022 - elifesciences.org
The most common cause of human congenital disorders of glycosylation (CDG) are
mutations in the phosphomannomutase gene PMM2, which affect protein N-linked …

Co-option of the same ancestral gene family gave rise to mammalian and reptilian toxins

A Barua, I Koludarov, AS Mikheyev - BMC biology, 2021 - Springer
Background Evolution can occur with surprising predictability when organisms face similar
ecological challenges. For most traits, it is difficult to ascertain whether this occurs due to …

Comparative genomics hints at dispensability of multiple essential genes in two Escherichia coli L-form strains

Y Liu, Y Zhang, C Kang, D Tian, H Lu, B Xu… - Bioscience …, 2023 - portlandpress.com
Despite the critical role of bacterial cell walls in maintaining cell shapes, certain
environmental stressors can induce the transition of many bacterial species into a wall …

Long-Term Adaptation to Galactose as a Sole Carbon Source Selects for Mutations Outside the Canonical GAL Pathway

AA Martínez, A Conboy, SW Buskirk, DA Marad… - Journal of Molecular …, 2023 - Springer
Galactose is a secondary fermentable sugar that requires specific regulatory and structural
genes for its assimilation, which are under catabolite repression by glucose. When glucose …

Long-term adaptation to galactose as a sole carbon source selects for mutations in nutrient signaling pathways

AA Martínez, A Conboy, SW Buskirk, DA Marad… - biorxiv, 2022 - biorxiv.org
Galactose is a secondary fermentable sugar that requires specific regulatory and structural
genes for its assimilation, which are under catabolite repression by glucose. When glucose …

Experimental evolution of phosphomannomutase-deficient yeast reveals compensatory mutations in a phosphoglucomutase

RC Vignogna, M Allocca, M Monticelli, JW Norris… - bioRxiv, 2022 - biorxiv.org
The most common cause of human congenital disorders of glycosylation (CDG) are
mutations in the phosphomannomutase gene PMM2, which affect protein N-linked …

An Empirical Analysis of Historical Contingency in Evolution

AJ Ferguson - 2024 - search.proquest.com
While evolution has created a stunning diversity of complex traits in nature, isolating the
details for how a particular trait evolved remains challenging. Specifically, what were the …

Co-occurrence of essential gene dispensability and bypass suppressor mutations across species

C Pons, J Leeuwen - bioRxiv, 2022 - biorxiv.org
Genes have been historically classified as either essential or non-essential based on their
requirement for viability. However, some genes are essential in some genetic backgrounds …