beta‐hydroxysteroid dehydrogenases (11β‐HSDs) catalyse the conversion of active 11‐
hydroxy glucocorticoids (cortisol, corticosterone) and their inert 11‐keto forms (cortisone, 11 …

Type 2 diabetes mellitus (T2DM), often featuring hyperglycemia or insulin resistance, is a
global health concern that is increasing in prevalence in the United States and worldwide. A …

Obesity is a serious medical condition that often co-occurs with stress-related psychiatric
disorders. It is recognized that the brain plays a key role in the (patho) physiology of obesity …

Medicinal plants of the genus Walsura (family Meliaceae) are native to tropical zones of a
number of Asian countries, and have been used in systems of folk medicine. Several original …

Obesity in childhood is associated with several steroid changes, which result from excess
body mass. The aim of this study was to evaluate steroid metabolism in children with obesity …

The present study carried out GC-MS analysis, antioxidant, antidiabetic, and ADMET study
of the crude ethanol extract (CRE), ethyl acetate (EAF), and aqueous (AQF) fractions of …

The 11 β-hydroxysteroid dehydrogenase 1 (11 β-HSD1) is hypothesized to play a role in the
pathogenesis of type 2 diabetes and its related complications. Because high glucocorticoid …

Pistacia lentiscus L.(P. lentiscus) is an evergreen shrub (Anacardiaceae family) primarily
found in the Mediterranean region. The plant has been thoroughly characterized, resulting in …

Background The combined effects of metformin and epigallocatechin-3-gallate (EGCG) on
cortisol, 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1), and blood glucose levels …

In the present study, an insulin-resistant cell model (human hepatocellular carcinoma cell
line: HepG2) was chosen to investigate the efficacy of two compound classes and their …