Angiotensin-converting enzyme (ACE) and its homologue, ACE2, have been mostly
associated with hypertensive disorder. However, recent pandemia of SARS-CoV-2 has put …

The aging population is increasing dramatically. Aging-associated stress simultaneously
drives proinflammatory remodeling, involving angiotensin II and other factors, in both the …

Covid19 is a worldwide pandemic challenge that started in Wuhan, China and spread to
almost all countries on the planet within a few months. The causative virus was found to be …

Humanity has always sought to live longer and for this, multiple strategies have been tried
with varying results. In this sense, G protein-coupled receptors (GPCRs) may be a good …

Background We have recently demonstrated that intrathecal (it) administration of
angiotensin II (A ng II) induces nociceptive behaviour in mice accompanied by a …

AIM To determine the effect of tempol in normal rats fed high salt on arterial pressure and the
balance between antagonist components of the renal renin-angiotensin system. METHODS …

Acromegaly is associated with an increased incidence of cardiovascular disease.
Transgenic mice expressing bovine GH (bGH) gene have previously been used to examine …

The renin–angiotensin system (RAS) plays a crucial role in the regulation of physiological
homeostasis and diseases such as hypertension, coronary artery disease, and chronic renal …

There is a sex difference in the hypothalamo-pituitary-adrenal (HPA) axis of many species,
although there are sparse data on the sheep. In the present study we have compared the …

We hypothesized that endothelial AT1‐activated NAD (P) H oxidase‐driven generation of
reactive oxygen species during type I‐diabetes impairs carotid ACE2‐angiotensin‐(1–7) …