Obesity is characterized by increased adipose tissue mass and has been associated with a
strong predisposition towards metabolic diseases and cancer. Thus, it constitutes a public …

Simple Summary Skeletal muscle mass is an important economic trait, and muscle
development and growth is a crucial factor to supply enough meat for human consumption …

Obesity and hyperlipidemia are the most prevalent independent risk factors of chronic
kidney disease (CKD), suggesting that lipid accumulation in the renal parenchyma is …

Adipogenesis is the process by which precursor stem cells differentiate into lipid laden
adipocytes. Adipogenesis is regulated by a complex and highly orchestrated gene …

There has been an upsurge of interest in the adipocyte coincident with the onset of the
obesity epidemic and the realization that adipose tissue plays a major role in the regulation …

Senescent cells accumulate in fat with aging. We previously found genetic clearance of
senescent cells from progeroid INK-ATTAC mice prevents lipodystrophy. Here we show that …

Understanding adipogenesis, the process of adipocyte development, may provide new ways
to treat obesity and related metabolic diseases. Adipogenesis is controlled by coordinated …

Adipose tissue, which is primarily composed of adipocytes, is crucial for maintaining energy
and metabolic homeostasis. Adipogenesis is thought to occur in two stages: commitment of …

Peroxisome proliferator-activated receptors (PPARs) are ligand-activated transcription
factors of nuclear hormone receptor superfamily comprising of the following three subtypes …

Fat tissue, frequently the largest organ in humans, is at the nexus of mechanisms involved in
longevity and age‐related metabolic dysfunction. Fat distribution and function change …