Exceptionally widespread nanomachines composed of type IV pilins: the prokaryotic Swiss Army knives

JL Berry, V Pelicic - FEMS microbiology reviews, 2015 - academic.oup.com
Prokaryotes have engineered sophisticated surface nanomachines that have allowed them
to colonize Earth and thrive even in extreme environments. Filamentous machineries …

Type IV pili: e pluribus unum?

V Pelicic - Molecular microbiology, 2008 - Wiley Online Library
The widespread role of pili as colonization factors in pathogens has long been recognized in
Gram‐negative bacteria and more recently in Gram‐positive bacteria, making the study of …

Architecture of the type IVa pilus machine

YW Chang, L Rettberg, A Treuner-Lange, J Iwasa… - Biophysical …, 2016 - cell.com
Type IV pili are part of a widespread superfamily of bacterial and archaeal cell surface
structures important for biofilm formation, motility, host adhesion, predation, DNA uptake …

PilY1 and minor pilins form a complex priming the type IVa pilus in Myxococcus xanthus

A Treuner-Lange, YW Chang, T Glatter… - Nature …, 2020 - nature.com
Type IVa pili are ubiquitous and versatile bacterial cell surface filaments that undergo cycles
of extension, adhesion and retraction powered by the cell-envelope spanning type IVa pilus …

The tad locus: postcards from the widespread colonization island

M Tomich, PJ Planet, DH Figurski - Nature Reviews Microbiology, 2007 - nature.com
The Tad (tight adherence) macromolecular transport system, which is present in many
bacterial and archaeal species, represents an ancient and major new subtype of type II …

Extracellular biology of Myxococcus xanthus

A Konovalova, T Petters… - FEMS microbiology …, 2010 - academic.oup.com
Myxococcus xanthus has a lifecycle characterized by several social interactions. In the
presence of prey, M. xanthus is a predator forming cooperatively feeding colonies, and in the …

A systematic genetic analysis in Neisseria meningitidis defines the Pil proteins required for assembly, functionality, stabilization and export of type IV pili

E Carbonnelle, S Helaine, X Nassif… - Molecular …, 2006 - Wiley Online Library
Although type IV pili (Tfp) are among the commonest virulence factors in bacteria, their
biogenesis by complex machineries of 12–15 proteins, and thereby their function remains …

Type IV pili‐dependent gliding motility in the Gram‐positive pathogen Clostridium perfringens and other Clostridia

JJ Varga, V Nguyen, DK O'Brien… - Molecular …, 2006 - Wiley Online Library
Bacteria can swim in liquid media by flagellar rotation and can move on surfaces via gliding
or twitching motility. One type of gliding motility involves the extension, attachment and …

Gliding motility revisited: how do the myxobacteria move without flagella?

EMF Mauriello, T Mignot, Z Yang… - … and Molecular Biology …, 2010 - Am Soc Microbiol
In bacteria, motility is important for a wide variety of biological functions such as virulence,
fruiting body formation, and biofilm formation. While most bacteria move by using …

Regulation of the type IV pili molecular machine by dynamic localization of two motor proteins

I Bulyha, C Schmidt, P Lenz, V Jakovljevic… - Molecular …, 2009 - Wiley Online Library
Summary Type IV pili (T4P) are surface structures that undergo extension/retraction
oscillations to generate cell motility. In Myxococcus xanthus, T4P are unipolarly localized …