Examination of whole organs with subcellular resolution in health, disease, and during
development is necessary to decipher their biological complexity. However, until recently …

The ability to image tissue morphogenesis in real-time and in 3-dimensions (3-D) remains
an optical challenge. The advent of light-sheet fluorescence microscopy (LSFM) has …

Light-sheet fluorescence microscopy (LSFM) is a minimally invasive and high throughput
imaging technique ideal for capturing large volumes of tissue with sub-cellular resolution. A …

The ocular vasculature is critically involved in many blinding diseases and is also a popular
research model for the exploration of developmental and pathological angiogenesis. The …

As the general population ages, more people are affected by eye diseases, such as
retinopathies. It is therefore critical to improve imaging of eye disease mouse models. Here …

Light-sheet fluorescence microscopy (LSFM) is a high-speed imaging technique that
provides optical sectioning with reduced photodamage. LSFM is routinely used in life …

The nitric oxide–guanylyl cyclase-1–cyclic guanylate monophosphate (NO–GC-1–cGMP)
pathway is integral to the control of vascular tone and morphology. Mice lacking the alpha …

Vascularization is a critical component of tissue engineering research and is essential for
enhancing the success rate of tissue construction and function. Over the past decade …

The successful investigation of photosensitive and dynamic biological events, such as those
in a proliferating tissue or a dividing cell, requires non-intervening high-speed imaging …

Stiffness-related eye diseases such as keratoconus require comprehensive visualization of
the complex morphological matrix changes. The aim of this study was to use three …