A critical review of uranium contamination in groundwater: treatment and sludge disposal

TP Gandhi, PV Sampath, SM Maliyekkal - Science of the Total Environment, 2022 - Elsevier
Dissolved uranium in groundwater at high concentrations is an emerging global threat to
human and ecological health due to its radioactivity and chemical toxicity. Uranium can …

Rational design of sequestering agents for plutonium and other actinides

AEV Gorden, J Xu, KN Raymond, P Durbin - Chemical reviews, 2003 - ACS Publications
Providing effective chelation therapy in response to internal human actinide contamination
has been shown to reduce acute radiation damage, chemical toxicity, and late radiation …

A 3, 2-hydroxypyridinone-based decorporation agent that removes uranium from bones in vivo

X Wang, X Dai, C Shi, J Wan, MA Silver… - Nature …, 2019 - nature.com
Searching for actinide decorporation agents with advantages of high decorporation
efficiency, minimal biological toxicity, and high oral efficiency is crucial for nuclear safety and …

Induction of lysosomal exocytosis and biogenesis via TRPML1 activation for the treatment of uranium-induced nephrotoxicity

D Zhong, R Wang, H Zhang, M Wang, X Zhang… - Nature …, 2023 - nature.com
Uranium (U) is a well-known nephrotoxicant which forms precipitates in the lysosomes of
renal proximal tubular epithelial cells (PTECs) after U-exposure at a cytotoxic dose …

Reproductive and developmental toxicity of natural and depleted uranium: a review

JL Domingo - Reproductive Toxicology, 2001 - Elsevier
Although the biokinetics, metabolism, and chemical toxicity of uranium are well known, until
recently little attention was paid to the potential toxic effects of uranium on reproduction and …

Nephrotoxicity of uranium: pathophysiological, diagnostic and therapeutic perspectives

L Vicente-Vicente, Y Quiros… - Toxicological …, 2010 - academic.oup.com
As in the case of other heavy metals, a considerable body of evidence suggests that
overexposure to uranium may cause pathological alterations to the kidneys in both humans …

Mechanism of in situ surface polymerization of gallic acid in an environmental-inspired preparation of carboxylated core–shell magnetite nanoparticles

IY Tóth, M Szekeres, R Turcu, S Sáringer, E Illés… - Langmuir, 2014 - ACS Publications
Magnetite nanoparticles (MNPs) with biocompatible coatings are good candidates for MRI
(magnetic resonance imaging) contrasting, magnetic hyperthermia treatments, and drug …

Prevention by chelating agents of metal-induced developmental toxicity

JL Domingo - Reproductive Toxicology, 1995 - Elsevier
Chelating agents such as calcium disodium ethylenediaminetetraacetate (EDTA), 2, 3-
dimercaptopropanol (BAL), or d-penicillamine (D-PA) have been widely used for the past 4 …

Uranium (VI) solubility and speciation in simulated elemental human biological fluids

M Sutton, SR Burastero - Chemical research in toxicology, 2004 - ACS Publications
The complete understanding of the human body response to uranium contamination
exposure is vital to the development of exposure analysis and subsequent treatments for …

The catecholic metal sequestering agent 1, 2-dihydroxybenzene-3, 5-disulfonate confers protection against oxidative cell damage

CM Krishna, JE Liebmann, D Kaufman… - Archives of biochemistry …, 1992 - Elsevier
Abstract Tiron (1, 2-dihydroxybenzene-3, 5-disulfonate), a non-toxic chelator of a variety of
metals, is used to alleviate acute metal overload in animals. It is also oxidized to the EPR …