Inteins: A Swiss army knife for synthetic biology
Inteins are proteins found in nature that execute protein splicing. Among them, split inteins
stand out for their versatility and adaptability, presenting creative solutions for addressing …
stand out for their versatility and adaptability, presenting creative solutions for addressing …
Electrochemical Sensors, Biosensors, and Optical Sensors for the Detection of Opioids and Their Analogs: Pharmaceutical, Clinical, and Forensic Applications
Pharmaceutical opioids are intravenously or orally administered analgesics. While they are
effective in relieving chronic and acute pain, their narrow window of therapeutic use …
effective in relieving chronic and acute pain, their narrow window of therapeutic use …
Design of a recombinant asparaginyl ligase for site-specific modification using efficient recognition and nucleophile motifs
J Tang, M Hao, J Liu, Y Chen, G Wufuer, J Zhu… - Communications …, 2024 - nature.com
Asparaginyl ligases have been extensively utilized as valuable tools for site-specific
bioconjugation or surface-modification. However, the application is hindered by the …
bioconjugation or surface-modification. However, the application is hindered by the …
Cell-Based Sensors for the Detection of EGF and EGF-Stimulated Ca2+ Signaling
Epidermal growth factor (EGF)-mediated activation of EGF receptors (EGFRs) has become
an important target in drug development due to the implication of EGFR-mediated cellular …
an important target in drug development due to the implication of EGFR-mediated cellular …
Split intein converting peptide protein interaction into electrochemically assisted metal ion catalytic signal in the prenatal screening of pediatric epilepsy
Y Guo, C Liu, F Qi, C Chen, Z Gao, H Zhang - Bioelectrochemistry, 2024 - Elsevier
Dravet syndrome is a rare form of epilepsy starting from infancy that can plaque the affected
individuals all though his/her life with repeated seizures, and this condition is currently …
individuals all though his/her life with repeated seizures, and this condition is currently …
Development of Ligand Assay Systems Using Semisynthetic Biosensors Based on Protein
N Nesakumar, AJ Kulandaisamy… - … and Applications in …, 2025 - Springer
A variety of biological substances and events in cells can be precisely detected and
monitored in real time using chemically fabricated biosensors composed of an artificial small …
monitored in real time using chemically fabricated biosensors composed of an artificial small …