[HTML][HTML] Prevalence of ESKAPE pathogens in the environment: Antibiotic resistance status, community-acquired infection and risk to human health

J Denissen, B Reyneke, M Waso-Reyneke… - International journal of …, 2022 - Elsevier
Abstract The ESKAPE (Enterococcus faecium, Staphylococcus aureus, Klebsiella
pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter spp.) …

Polymyxin and lipopeptide antibiotics: membrane-targeting drugs of last resort

EVK Ledger, A Sabnis, AM Edwards - Microbiology, 2022 - microbiologyresearch.org
The polymyxin and lipopeptide classes of antibiotics are membrane-targeting drugs of last
resort used to treat infections caused by multi-drug-resistant pathogens. Despite similar …

Structure–activity relationships of daptomycin lipopeptides

JA Karas, GP Carter, BP Howden… - Journal of medicinal …, 2020 - ACS Publications
Daptomycin is a calcium-dependent cyclic lipodepsipeptide derived from the soil saprotroph
Streptomyces roseosporus, and its antibiotic properties make it a key agent for treatment of …

Bacterial cell membranes and their role in daptomycin resistance: A review

AH Nguyen, KS Hood, E Mileykovskaya… - Frontiers in Molecular …, 2022 - frontiersin.org
Lipids play a major role in bacterial cells. Foremost, lipids are the primary constituents of the
cell membrane bilayer, providing structure and separating the cell from the surrounding …

Nationwide Surveillance on Antimicrobial Resistance Profiles of Enterococcus faecium and Enterococcus faecalis Isolated from Healthy Food Animals in South …

MH Kim, DC Moon, SJ Kim, AF Mechesso, HJ Song… - Microorganisms, 2021 - mdpi.com
Intestinal commensal bacteria are considered good indicators for monitoring antimicrobial
resistance. We investigated the antimicrobial resistance profiles and resistance trends of …

Genomic Insights Into Last-Line Antimicrobial Resistance in Multidrug-Resistant Staphylococcus and Vancomycin-Resistant Enterococcus

AM Turner, JYH Lee, CL Gorrie, BP Howden… - Frontiers in …, 2021 - frontiersin.org
Multidrug-resistant Staphylococcus and vancomycin-resistant Enterococcus (VRE) are
important human pathogens that are resistant to most clinical antibiotics. Treatment options …

Evolution of vancomycin-resistant Enterococcus faecium during colonization and infection in immunocompromised pediatric patients

GS Chilambi, HR Nordstrom… - Proceedings of the …, 2020 - National Acad Sciences
Patients with hematological malignancies or undergoing hematopoietic stem cell
transplantation are vulnerable to colonization and infection with multidrug-resistant …

Cross-regulation of Aps-promoters in Lacticaseibacillus paracasei by the PsdR response regulator in response to lantibiotics

Q Zhang, M Zúñiga, C Alcántara, D Wolf, T Mascher… - Scientific reports, 2024 - nature.com
Abstract The PsdRSAB and ApsRSAB detoxification modules, together with the antimicrobial
peptides (AMPs)-resistance determinants Dlt system and MprF protein, play major roles in …

Antibiotic resistance determination using Enterococcus faecium whole-genome sequences: a diagnostic accuracy study using genotypic and phenotypic data

F Coll, T Gouliouris, B Blane, CA Yeats… - The Lancet …, 2024 - thelancet.com
Background DNA sequencing could become an alternative to in vitro antibiotic susceptibility
testing (AST) methods for determining antibiotic resistance by detecting genetic …

Daptomycin Resistance Occurs Predominantly in vanA-Type Vancomycin-Resistant Enterococcus faecium in Australasia and Is Associated With Heterogeneous and …

L Li, C Higgs, AM Turner, Y Nong, CL Gorrie… - Frontiers in …, 2021 - frontiersin.org
Healthcare associated infections caused by vancomycin-resistant Enterococcus faecium
(VREfm) have a major impact on health outcomes. VREfm is difficult to treat because of …