Investigating the preferential interaction between imatinib mesylate and VEGF G-quadruplex DNA as therapeutic strategies for cancer treatment: Biophysical and …

S Ghosal, S Bag, RK Chinnadurai, M Mukherjee… - Computers in Biology …, 2024 - Elsevier
G-Quadruplex DNA (GQ–DNA) is one of the most important non-canonical nucleic acid
structures. GQ–DNA forming sequences are present in different crucial genomic regions and …

Heavy metal ions interactions with G-quadruplex-prone DNA sequences

SA Mehrdad, A Cucchiarini, JL Mergny, SK Noureini - Biochimie, 2024 - Elsevier
The industrial world exposes living organisms to a variety of metal pollutants. Here we
investigated whether such elements affect G-rich sequences susceptible to fold into G …

Non‐Innocent π Linkers Affect Cooperativity in Hydrogen‐Bonded Macrocycles

D Almacellas, SCC van der Lubbe, AA Grosch… - …, 2024 - Wiley Online Library
Rigid, linear π‐conjugated acetylene linkers connecting a hydrogen‐bond acceptor to a
hydrogen‐bond donor are established building blocks for self‐assembled hydrogen …

Cooperativity in Hydrogen‐Bonded Macrocycles Derived from Nucleobases

D Almacellas, SCC van der Lubbe… - European Journal of …, 2024 - Wiley Online Library
Introducing a rigid linear π‐conjugated acetylene linker into a supramolecular building block
consisting of a hydrogen‐bond donor side and a hydrogen‐bond acceptor side yields a …

G-Quadruplexes Formation by the C9orf72 Nucleotide Repeat Expansion d(GGGGCC)n and Conformation Regulation by Fangchinoline

Y Zhang, J Huang, K Yu, X Cui - Molecules, 2023 - mdpi.com
The G-quadruplex (GQ)-forming hexanucleotide repeat expansion (HRE) in the C9orf72
(C9) gene has been found to be the most common cause of amyotrophic lateral sclerosis …