The metabolic, virulence and antimicrobial resistance profiles of colonising Streptococcus pneumoniae shift after PCV13 introduction in urban Malawi
Streptococcus pneumoniae causes substantial mortality among children under 5-years-old
worldwide. Polysaccharide conjugate vaccines (PCVs) are highly effective at reducing …
worldwide. Polysaccharide conjugate vaccines (PCVs) are highly effective at reducing …
Puzzling over the pneumococcal pangenome
The Gram positive bacterium Streptococcus pneumoniae (pneumococcus) is a major human
pathogen. It is a common colonizer of the human host, and in the nasopharynx, sinus, and …
pathogen. It is a common colonizer of the human host, and in the nasopharynx, sinus, and …
Antimicrobial resistance in Streptococcus pneumoniae: a retrospective analysis of emerging trends in the United Arab Emirates from 2010 to 2021
Introduction Although pneumococcal conjugate vaccines (PCV) have been effective in
reducing the burden of Streptococcus pneumoniae infections, there is a paucity of data on …
reducing the burden of Streptococcus pneumoniae infections, there is a paucity of data on …
Increased pathogenicity of pneumococcal serotype 1 is driven by rapid autolysis and release of pneumolysin
LC Jacques, S Panagiotou, M Baltazar… - Nature …, 2020 - nature.com
Streptococcus pneumoniae serotype 1 is the predominant cause of invasive pneumococcal
disease in sub-Saharan Africa, but the mechanism behind its increased invasiveness is not …
disease in sub-Saharan Africa, but the mechanism behind its increased invasiveness is not …
The role of interspecies recombination in the evolution of antibiotic-resistant pneumococci
JC D'Aeth, MPG van der Linden, L McGee… - Elife, 2021 - elifesciences.org
Multidrug-resistant Streptococcus pneumoniae emerge through the modification of core
genome loci by interspecies homologous recombinations, and acquisition of gene cassettes …
genome loci by interspecies homologous recombinations, and acquisition of gene cassettes …
Streptococcus pneumoniae serotypes that frequently colonise the human nasopharynx are common recipients of penicillin-binding protein gene fragments from …
Streptococcus pneumoniae is an important global pathogen that causes bacterial
pneumonia, sepsis and meningitis. Beta-lactam antibiotics are the first-line treatment for …
pneumonia, sepsis and meningitis. Beta-lactam antibiotics are the first-line treatment for …
Continued occurrence of serotype 1 pneumococcal meningitis in two regions located in the meningitis belt in Ghana five years after introduction of 13-valent …
CH Bozio, A Abdul-Karim, J Abenyeri, B Abubakari… - PloS one, 2018 - journals.plos.org
Background Increases in pneumococcal meningitis were reported from Ghanaian regions
that lie in the meningitis belt in 2016–2017, despite introduction of 13-valent pneumococcal …
that lie in the meningitis belt in 2016–2017, despite introduction of 13-valent pneumococcal …
Antimicrobial susceptibility, serotype distribution, virulence profile and molecular typing of piliated clinical isolates of pneumococci from east coast, Peninsular …
Pilus has been recently associated with pneumococcal pathogenesis in humans. The
information regarding piliated isolates in Malaysia is scarce, especially in the less …
information regarding piliated isolates in Malaysia is scarce, especially in the less …
[HTML][HTML] Pilus islets and the clonal spread of piliated Streptococcus pneumoniae: A review
Pneumococci are a common cause of severe infections, such as otitis media, pneumonia,
meningitis and bacteremia. Pili are detected in a small proportion of pneumococcal …
meningitis and bacteremia. Pili are detected in a small proportion of pneumococcal …
Whole-genome sequencing analysis of multidrug-resistant serotype 15A Streptococcus pneumoniae in Japan and the emergence of a highly resistant serotype 15A …
S Nakano, T Fujisawa, Y Ito, B Chang… - Antimicrobial Agents …, 2019 - Am Soc Microbiol
Since the introduction of pneumococcal conjugate vaccines (PCVs), an increase in the
incidence of disease attributable to serotype 15A-ST63 (sequence type 63) pneumococci …
incidence of disease attributable to serotype 15A-ST63 (sequence type 63) pneumococci …