Liver transplantation plus chemotherapy versus chemotherapy alone in patients with permanently unresectable colorectal liver metastases (TransMet): results from a …
Background Despite the increasing efficacy of chemotherapy, permanently unresectable
colorectal liver metastases are associated with poor long-term survival. We aimed to assess …
colorectal liver metastases are associated with poor long-term survival. We aimed to assess …
Clinical research progress on BRAF V600E-mutant advanced colorectal cancer
C Zeng, M Wang, S Xie, N Wang, Z Wang, D Yi… - Journal of Cancer …, 2023 - Springer
Colorectal cancer is one of the malignant tumors that pose a serious threat to human health.
A particularly bad prognosis might be expected for colorectal tumors with the unique …
A particularly bad prognosis might be expected for colorectal tumors with the unique …
[HTML][HTML] A meta-analysis of efficacy and safety data from head-to-head first-line trials of epidermal growth factor receptor inhibitors versus bevacizumab in adult …
T Yoshino, N Hooda, D Younan, K Muro… - European Journal of …, 2024 - Elsevier
The first-line treatment choice of EGFRIs plus doublet chemotherapy vs. bevacizumab plus
doublet chemotherapy remains a topic of interest for patients with left-sided RAS WT mCRC …
doublet chemotherapy remains a topic of interest for patients with left-sided RAS WT mCRC …
Circular RNA ACVR2A promotes the progression of hepatocellular carcinoma through mir-511-5p targeting PI3K-Akt signaling pathway
D Fei, F Wang, Y Wang, J Chen, S Chen, L Fan… - Molecular Cancer, 2024 - Springer
Circular RNA (circRNA) is thought to mediate the occurrence and development of human
cancer and usually acts as a tiny RNA (miRNA) sponge to regulate downstream gene …
cancer and usually acts as a tiny RNA (miRNA) sponge to regulate downstream gene …
Cancer treatment monitoring using cell-free DNA fragmentomes
Circulating cell-free DNA (cfDNA) assays for monitoring individuals with cancer typically rely
on prior identification of tumor-specific mutations. Here, we develop a tumor-independent …
on prior identification of tumor-specific mutations. Here, we develop a tumor-independent …
Combined hepatic arterial infusion pump and systemic chemotherapy in the modern era for chemotherapy-naive patients with unresectable colorectal liver metastases
FS Verheij, KFD Kuhlmann, DR Silliman… - Annals of Surgical …, 2023 - Springer
Purpose Chemotherapy-naive patients with unresectable colorectal liver metastases
(CRLM) have been the best responders to hepatic arterial infusion (HAI) therapy. The …
(CRLM) have been the best responders to hepatic arterial infusion (HAI) therapy. The …
First-line systemic treatment for initially unresectable colorectal liver metastases: post hoc analysis of the CAIRO5 randomized clinical trial
MJG Bond, K Bolhuis, OJL Loosveld… - JAMA …, 2025 - jamanetwork.com
Importance In patients with colorectal cancer and unresectable liver-only metastases
(CRLM), treatment with folinic acid, fluorouracil, and oxaliplatin (FOLFOX) plus irinotecan …
(CRLM), treatment with folinic acid, fluorouracil, and oxaliplatin (FOLFOX) plus irinotecan …
Nucleus-translocated GCLM promotes chemoresistance in colorectal cancer through a moonlighting function
JF Lin, ZX Liu, DL Chen, RZ Huang, F Cao… - Nature …, 2025 - nature.com
Metabolic enzymes perform moonlighting functions during tumor progression, including the
modulation of chemoresistance. However, the underlying mechanisms of these functions …
modulation of chemoresistance. However, the underlying mechanisms of these functions …
Safety of first-line systemic therapy in patients with metastatic colorectal cancer: a network meta-analysis of randomized controlled trials
Y Zhan, X Cheng, P Mei, S Tan, W Feng, H Jiang - BMC cancer, 2024 - Springer
Objective To evaluate the safety of first-line systemic therapy for metastatic colorectal cancer
through network meta-analysis. Methods The literature from PubMed, Embase, Web of …
through network meta-analysis. Methods The literature from PubMed, Embase, Web of …
CSCO guidelines for colorectal cancer version 2024: Updates and discussions
L Chen, H Hu, Y Yuan, S Weng - Chinese Journal of Cancer …, 2024 - pmc.ncbi.nlm.nih.gov
CSCO guidelines for colorectal cancer version 2024: Updates and discussions - PMC Skip to
main content Here's how you know Official websites use .gov A .gov website belongs to an …
main content Here's how you know Official websites use .gov A .gov website belongs to an …