Recent human and animal model experimental studies revealed novel pathways for fluid
movement, immune cell trafficking and metabolic waste clearance in CNS. These studies …

Background Postoperative delirium (POD) is a frequent neurologic dysfunction that often
leads to more negative outcomes. Early identification of patients who are vulnerable to POD …

The association between Alzheimer's disease (AD) and type 2 diabetes mellitus (T2DM) has
been extensively demonstrated, but despite this, the pathophysiological mechanisms …

Background Mounting evidence links glucose intolerance and diabetes as aspects of
metabolic dysregulation that are associated with an increased risk of developing dementia …

The lack of effective treatments for dementia has led to explore the potential of antidiabetic
agents as a possible approach. This cross-sectional and population-based study aimed to …

Introduction Many studies have revealed the effect of medical history on dementia. The aim
of this study was to explore the relationship between the history of disease and onset of …

Malnutrition, hypercatabolism, and metabolic changes are well-established risk factors for
delirium in critically ill patients. Although the exact mechanisms are not fully understood …

Introduction Guidelines recommend screening older people (> 60–65 years) with type 2
diabetes (T2D) for cognitive impairment, as it has implications in the management of …

Alzheimer's disease (AD) is a progressive neurodegenerative disorder and leading cause of
dementia, characterized by neuronal and synapse loss, amyloid-β and tau protein …

An estimated 55 million people worldwide suffer from dementia, with the prevalence
expected to drastically increase in the coming years as the population ages. Alzheimer's …