The purpose of this report is to review the literature regarding spinal cord compression in
mucopolysaccharidosis type VI (MPS VI), to discuss the possible impact of enzyme …

OBJECTIVE: To study the efficacy and safety of intrathecal baclofen therapy (ITB) in
wheelchair-dependent adults with cerebral palsy. PATIENTS AND METHODS: A …

Opisthotonus refers to abnormal axial extension and arching of the trunk produced by
excessive contractions of the paraspinal muscles. In childhood, the abnormal posture is …

Continuous infusion of baclofen is a treatment option for severe generalized dystonia.
Catheter insertion within the third ventricle has been described as an alternative to standard …

Klippel–Feil syndrome (KFS) is characterized by the congenital fusion of the cervical
vertebrae and is sometimes accompanied by anomalies in the craniocervical junction. In …

Cerebral palsy is a complex disease process that impacts the lifespan of a child, an
adolescent, and an adult, as well as the family/caregiver dynamic. Clinicians can optimize …

Objective: To identify changes in weight for children receiving intrathecal baclofen (ITB)
therapy for the treatment of spasticity. Design: Retrospective medical chart review. Weights …

Spasticity of cerebral or spinal origin severely impairs an individual's functional ability and
quality of life. Intrathecal baclofen (ITB) therapy via an implantable pump is indicated for use …

Objectives: Identify the etiology of opisthotonus and the medical conditions associated with
it. Outline the appropriate evaluation of patients presenting with opisthotonus. Review the …

Metoclopramide is widely used as an antiemetic and a prokinetic agent. Both the antiemetic
properties and side effects of the drug are the result of dopamine receptor antagonism within …