Acute respiratory distress syndrome

MA Matthay, RL Zemans, GA Zimmerman… - Nature reviews Disease …, 2019 - nature.com
The acute respiratory distress syndrome (ARDS) is a common cause of respiratory failure in
critically ill patients and is defined by the acute onset of noncardiogenic pulmonary oedema …

The superoxide radical switch in the biology of nitric oxide and peroxynitrite

L Piacenza, A Zeida, M Trujillo… - Physiological …, 2022 - journals.physiology.org
The free radical nitric oxide (· NO) is a key mediator in different physiological processes such
as vasodilation, neurotransmission, inflammation, and cellular immune responses, and thus …

Role of inflammatory mediators in the pathophysiology of acute respiratory distress syndrome

M Bhatia, S Moochhala - The Journal of Pathology: A Journal of …, 2004 - Wiley Online Library
Inflammatory response leading to organ dysfunction and failure continues to be the major
problem after injury in many clinical conditions such as sepsis, severe burns, acute …

Biomarkers in acute lung injury

D Mokra, P Kosutova - Respiratory physiology & neurobiology, 2015 - Elsevier
Acute respiratory distress syndrome (ARDS) and its milder form acute lung injury (ALI) may
result from various diseases and situations including sepsis, pneumonia, trauma, acute …

Lung epithelial fluid transport and the resolution of pulmonary edema

MA Matthay, HG Folkesson… - Physiological reviews, 2002 - journals.physiology.org
The discovery of mechanisms that regulate salt and water transport by the alveolar and
distal airway epithelium of the lung has generated new insights into the regulation of lung …

Proteins as biomarkers of oxidative/nitrosative stress in diseases: the contribution of redox proteomics

I Dalle‐Donne, A Scaloni, D Giustarini… - Mass spectrometry …, 2005 - Wiley Online Library
Abstract I. Introduction 00 II. Reactive Oxygen and Nitrogen Species 00 III. Biological
Markers of Oxidative/Nitrosative Stress 00 IV. Oxidative/Nitrosative Stress and Protein …

Transepithelial migration of neutrophils: mechanisms and implications for acute lung injury

RL Zemans, SP Colgan, GP Downey - American journal of …, 2009 - atsjournals.org
The primary function of neutrophils in host defense is to contain and eradicate invading
microbial pathogens. This is achieved through a series of swift and highly coordinated …

Methods of detection of vascular reactive species: nitric oxide, superoxide, hydrogen peroxide, and peroxynitrite

MM Tarpey, I Fridovich - Circulation research, 2001 - Am Heart Assoc
The evanescent nature of reactive oxygen and nitrogen species, the multiple cellular
mechanisms evolved to maintain these substances at low (submicromolar) concentrations …

An official American Thoracic Society research statement: noninfectious lung injury after hematopoietic stem cell transplantation: idiopathic pneumonia syndrome

A Panoskaltsis-Mortari, M Griese… - American journal of …, 2011 - atsjournals.org
Rationale: Acute lung dysfunction of noninfectious etiology, known as idiopathic pneumonia
syndrome (IPS), is a severe complication following hematopoietic stem cell transplantation …

Acute lung injury review

K Tsushima, LS King, NR Aggarwal, A De Gorordo… - Internal …, 2009 - jstage.jst.go.jp
The first report of acute respiratory distress syndrome (ARDS) was published in 1967, and
even now acute lung injury (ALI) and ARDS are severe forms of diffuse lung disease that …