Parkinson's disease (PD) is the second most common neurodegenerative disorder. The
degeneration of dopaminergic neurons in the midbrain is primarily responsible for the onset …

The prevalence of neurological/neurodegenerative diseases, such as Alzheimer's disease is
known to be increasing due to an aging population and is anticipated to further grow in the …

Vesicular drug delivery carriers, a subgroup of colloidal drug delivery systems (CDDS), can
be defined as highly ordered assemblies consisting of one or more concentric bilayers …

Parkinson's disease is a neurodegenerative disease, the treatment of which is mainly
centred around supplementation of dopamine. Additional targets have been identified and …

Abstract “Neurodegenerative disease” is a term for a variety of disorders that primarily affect
neurons in the human brain and spinal cord. These diseases are presently incurable and …

Central nervous system (CNS)-related disease treatments using pharmaceuticals lack
therapeutic efficacy due to unknown pathologies and the inability of remedies to pass …

ABSTRACT Background Current medications for Parkinson's disease (PD) primarily offer
symptomatic relief, and often lead to adverse effects on long-term use. This highlights the …

ABSTRACT Objective (s): Currently, the development of nanoparticles for the stabilization
and targeted delivery of cardiac drugs has gained significance. The present study aimed to …

RESUMO A esclerose múltipla (EM) é uma doença autoimune, crônica e progressiva
caracterizada por infiltrado inflamatório, gliose, desmielinização e degeneração axonal no …

Objectives: Epidemiological data suggests the highest density of histamine H3-receptors
(H3R) in basal ganglia of central nervous system (CNS) wherein they function as inhibitory …