[HTML][HTML] Digitization of pathology labs: a review of lessons learned

LO Schwen, TR Kiehl, R Carvalho, N Zerbe… - Laboratory …, 2023 - Elsevier
Pathology laboratories are increasingly using digital workflows. This has the potential of
increasing lab efficiency, but the digitization process also involves major challenges …

The Human Body as an Ethanol-Producing Bioreactor—The Forensic Impacts

I Šoša - Fermentation, 2023 - mdpi.com
Auto-brewery syndrome (ABS), also called gut fermentation syndrome, is an extremely
infrequent but also underrecognized disorder where ethanol is produced endogenously …

Transcriptomics-guided slide representation learning in computational pathology

G Jaume, L Oldenburg, A Vaidya… - Proceedings of the …, 2024 - openaccess.thecvf.com
Self-supervised learning (SSL) has been successful in building patch embeddings of small
histology images (eg 224 x 224 pixels) but scaling these models to learn slide embeddings …

Application of multiple-finding segmentation utilizing Mask R-CNN-based deep learning in a rat model of drug-induced liver injury

EB Baek, J Lee, JH Hwang, H Park, BS Lee, YB Kim… - Scientific Reports, 2023 - nature.com
Drug-induced liver injury (DILI) presents significant diagnostic challenges, and recently
artificial intelligence-based deep learning technology has been used to predict various …

A comparative study on the implementation of deep learning algorithms for detection of hepatic necrosis in toxicity studies

JH Hwang, M Lim, G Han, H Park, YB Kim, J Park… - Toxicological …, 2023 - Springer
Deep learning has recently become one of the most popular methods of image analysis. In
non-clinical studies, several tissue slides are generated to investigate the toxicity of a test …

Preparing pathological data to develop an artificial intelligence model in the nonclinical study

JH Hwang, M Lim, G Han, H Park, YB Kim, J Park… - Scientific Reports, 2023 - nature.com
Artificial intelligence (AI)-based analysis has recently been adopted in the examination of
histological slides via the digitization of glass slides using a digital scanner. In this study, we …

[HTML][HTML] Advancements in pathology: Digital transformation, precision medicine, and beyond

S Ahuja, S Zaheer - Journal of Pathology Informatics, 2024 - Elsevier
Pathology, a cornerstone of medical diagnostics and research, is undergoing a revolutionary
transformation fueled by digital technology, molecular biology advancements, and big data …

[HTML][HTML] Accelerating pharmaceutical R&D with a user-friendly AI system for histopathology image analysis

B Lutnick, AJ Ramon, B Ginley, C Csiszer, A Kim… - Journal of Pathology …, 2023 - Elsevier
A system for analysis of histopathology data within a pharmaceutical R&D environment has
been developed with the intention of enabling interdisciplinary collaboration. State-of-the-art …

Machine learning in toxicological sciences: opportunities for assessing drug toxicity

L Tonoyan, AG Siraki - Frontiers in Drug Discovery, 2024 - frontiersin.org
Machine learning (ML) in toxicological sciences is growing exponentially, which presents
unprecedented opportunities and brings up important considerations for using ML in this …

Morphologic Features and Deep Learning–Based Analysis of Canine Spermatogenic Stages

S Mehrvar, T Kambara - Toxicologic Pathology, 2022 - journals.sagepub.com
In nonclinical toxicity studies, stage-aware evaluation is often expected to assess drug-
induced testicular toxicity. Although stage-aware evaluation does not require identification of …