Honey bee and bumble bee antiviral defense

AJ McMenamin, KF Daughenbaugh, F Parekh… - Viruses, 2018 - mdpi.com
Bees are important plant pollinators in both natural and agricultural ecosystems. Managed
and wild bees have experienced high average annual colony losses, population declines …

Sensing and signalling viral infection in drosophila

J Schneider, JL Imler - Developmental & Comparative Immunology, 2021 - Elsevier
The fruitfly Drosophila melanogaster is a valuable model to unravel mechanisms of innate
immunity, in particular in the context of viral infections. RNA interference, and more …

Interferon functional analog activates antiviral Jak/Stat signaling through integrin in an arthropod

J Gao, BR Zhao, H Zhang, YL You, F Li, XW Wang - Cell reports, 2021 - cell.com
Drosophila Vago is a small antiviral peptide. Its ortholog in Culex mosquito was found to be
an interferon-like cytokine that limits virus replication through activating Jak/Stat signaling …

RNAi in insects: a revolution in fundamental research and pest control applications

O Christiaens, J Niu, C Nji Tizi Taning - Insects, 2020 - mdpi.com
In this editorial for the Special Issue on 'RNAi in insect pest control', three important
applications of RNA interference (RNAi) in insects are briefly discussed and linked to the …

Risk assessment of RNAi-based pesticides to non-target organisms: evaluating the effects of sequence similarity in the parasitoid wasp Telenomus podisi

NL Castellanos, G Smagghe, CNT Taning… - Science of the Total …, 2022 - Elsevier
RNA interference (RNAi)-based pesticides are promising novel pest management products
that might reduce environmental impacts compared to other pesticides. Their sequence …

Generation of virus-and dsRNA-derived siRNAs with species-dependent length in insects

D Santos, L Mingels, E Vogel, L Wang, O Christiaens… - Viruses, 2019 - mdpi.com
Double-stranded RNA (dsRNA) molecules of viral origin trigger a post-transcriptional gene-
silencing mechanism called RNA interference (RNAi). Specifically, virally derived dsRNA is …

A myeloid differentiation–like protein in partnership with Toll5 from the pest insect Spodoptera litura senses baculovirus infection

R Zhang, J Zhong, Y Li, M Li, J Zhang, Q Hu… - Proceedings of the …, 2024 - pnas.org
Many types of viruses infect insects and other arthropods. In contrast, little is known about
how arthropods sense viruses, although several innate immune pathways including Toll …

A single von Willebrand factor C-domain protein acts as an extracellular pattern-recognition receptor in the river prawn Macrobrachium nipponense

N Qin, H Sun, M Lu, J Wang, T Tang, F Liu - Journal of Biological Chemistry, 2020 - ASBMB
The single von Willebrand factor C-domain proteins (SVWCs) are mainly found in
arthropods. Their expression may be regulated by several environmental stresses, including …

Heterologous expression of the insect SVWC peptide WHIS1 inhibits Candida albicans invasion into A549 and HeLa epithelial cells

M Chen, WK Huang, Y Yao, SM Wu, YX Yang… - Frontiers in …, 2024 - frontiersin.org
Candida albicans (C. albicans), a microbe commonly isolated from Candida vaginitis
patients with vaginal tract infections, transforms from yeast to hyphae and produces many …

Transcriptomic Analysis of Aedes aegypti Innate Immune System in Response to Ingestion of Chikungunya Virus

L Zhao, BW Alto, Y Jiang, F Yu, Y Zhang - International Journal of …, 2019 - mdpi.com
Aedes aegypti (L.) is the primary vector of emergent mosquito-borne viruses, including
chikungunya, dengue, yellow fever, and Zika viruses. To understand how these viruses …