Nanomedical approaches in the realm of rheumatoid arthritis

AF Radu, SG Bungau - Ageing research reviews, 2023 - Elsevier
Rheumatoid arthritis (RA) is a heterogeneous autoimmune inflammatory disorder defined by
the damage to the bone and cartilage in the synovium, which causes joint impairment and …

The role of glucocorticoids in inflammatory diseases

SD Reichardt, A Amouret, C Muzzi, S Vettorazzi… - Cells, 2021 - mdpi.com
For more than 70 years, glucocorticoids (GCs) have been a powerful and affordable
treatment option for inflammatory diseases. However, their benefits do not come without a …

Quality by design-driven zeta potential optimisation study of liposomes with charge imparting membrane additives

Z Németh, I Csóka, R Semnani Jazani, B Sipos… - Pharmaceutics, 2022 - mdpi.com
Liposomal formulations, as versatile nanocarrier systems suitable for targeted delivery, have
a highly focused role in the therapy development of unmet clinical needs and diagnostic …

[HTML][HTML] Nanomedicines for the treatment of rheumatoid arthritis: State of art and potential therapeutic strategies

Q Wang, X Qin, J Fang, X Sun - Acta Pharmaceutica Sinica B, 2021 - Elsevier
Increasing understanding of the pathogenesis of rheumatoid arthritis (RA) has remarkably
promoted the development of effective therapeutic regimens of RA. Nevertheless, the …

Advanced nanomedicines for the treatment of inflammatory diseases

R Brusini, M Varna, P Couvreur - Advanced drug delivery reviews, 2020 - Elsevier
Inflammation, a common feature of many diseases, is an essential immune response that
enables survival and maintains tissue homeostasis. However, in some conditions, the …

Biomedical nanomaterials for immunological applications: ongoing research and clinical trials

V Lenders, X Koutsoumpou, A Sargsian… - Nanoscale …, 2020 - pubs.rsc.org
Research efforts on nanomaterial-based therapies for the treatment of autoimmune diseases
and cancer have spiked and have made rapid progress over the past years. Nanomedicine …

Active targeted nanoformulations via folate receptors: State of the art and future perspectives

C Martín-Sabroso, AI Torres-Suárez… - Pharmaceutics, 2021 - mdpi.com
In normal tissues, the expression of folate receptors is low and limited to cells that are
important for embryonic development or for folate reabsorption. However, in several …

Nanotechnology-empowered combination therapy for rheumatoid arthritis: principles, strategies, and challenges

S Ren, Y Xu, X Dong, Q Mu, X Chen, Y Yu… - Journal of …, 2024 - Springer
Rheumatoid arthritis (RA) is an autoimmune disease with multifactorial etiology and intricate
pathogenesis. In RA, repeated monotherapy is frequently associated with inadequate …

Rheumatoid arthritis: Pathophysiology, current therapeutic strategies and recent advances in targeted drug delivery system

R Deshmukh - Materials Today Communications, 2023 - Elsevier
Recent advancements in technology and science thoroughly changed the basic
understanding and treatment approach of rheumatoid arthritis (RA). RA is a chronic …

Recent progress in therapeutic strategies and biomimetic nanomedicines for rheumatoid arthritis treatment

C Li, X Zheng, M Hu, M Jia, R Jin… - Expert opinion on drug …, 2022 - Taylor & Francis
Introduction Rheumatoid arthritis (RA) is an autoimmune systemic disease in which
inflammatory and immune cells accumulate in inflamed joints. Researchers aimed at the …