The epithelial-mesenchymal transition (EMT) represents a biological program during which
epithelial cells lose their cell identity and acquire a mesenchymal phenotype. EMT is …

The epithelial to mesenchymal transition (EMT) is a biological process in which a non-motile
epithelial cell changes to a mesenchymal phenotype with invasive capacities. This …

Metastasis of tumor cells from primary sites of malignancy to neighboring stromal tissue or
distant localities entails in several instances, but not in every case, the epithelial …

Simple Summary Given the importance of the epithelial-to-mesenchymal transition in tumor
progression and the pivotal role of ZEB1 as a transcriptional repressor during this process …

Post-translational modification (PTM), the essential regulatory mechanisms of proteins, play
essential roles in physiological and pathological processes. In addition, PTM functions in …

Cholangiocarcinoma is one of the epithelial cancers with the poorest prognosis and the
narrowest therapeutic choice in humans. Compared with other cancer types …

Neuroblastoma (NB) is the most common malignant tumor in infancy and most common
extracranial solid tumor in childhood. With the improvement of diagnosis and treatment, the …

Abstract Background Targeting protein for Xklp2 (TPX2) is a microtubule-associated protein
involved in targeting the motor protein Xklp2 to microtubules. TPX2 overexpression plays a …

Human HLA-F adjacent transcript 10 (FAT10) is the only ubiquitin-like protein that can
directly target substrates for degradation by proteasomes, but it can also stabilize the …

Background Basal-like breast cancer (BLBC) is one of the most aggressive malignant
diseases in women with an increased metastatic behavior and poor prognosis compared to …