The growing emergence of multidrug resistant tuberculosis (MDR-TB) strains is obstructing
efforts for the control and management of TB. Proper management of MDR-TB relies on …

Recently, the need for rapid, reliable, and low-cost drug susceptibility testing (DST) methods
has increased due to the emergence of multidrug-resistant Mycobacterium tuberculosis …

Background: The overexpression of efflux pumps (Eps) was reported to contribute to
multidrug resistant tuberculosis (MDR-TB). Increases in Eps that expel structurally unrelated …

Mycobacterium tuberculosis (Mtb), an acid-fast bacillus that causes Tuberculosis (TB), is a
pathogen that caused 1.5 million deaths in 2020. As per WHO estimates, another 4.1 million …

Aims and objectives: Current methods for drug susceptibility testing (DST) of Mycobacterium
tuberculosis (MTB) are either costly or slow. As the prevalence of multidrug-resistant (MDR) …

Methods: A total of 116 Mycobacterium tuberculosis isolates were used to assess the
mutations in the gyrA, gyrB genes and resistance levels to OFX. Mutational analysis in gyrA …

Background Emergence of multi-drug-resistant tuberculosis is a serious challenge for
successful global tuberculosis control. Early diagnosis of drug-resistant tuberculosis by …

Objective: To evaluate the performance of nitrate reductase assay on smear positive
pulmonary specimens for detection of multi and extensively drug resistant tuberculosis …

Introduction: Reports of Mycobacterium tuberculosis resistant to multiple drugs are
increasing globally and laboratories are becoming increasingly aware of the need for drug …

T uberculosis has been one of the deadliest infectious diseases in the world and remains a
public health threat (1). In 2018, the World Health Organization reported more than 10 …