Determinants of genetic diversity

H Ellegren, N Galtier - Nature Reviews Genetics, 2016 - nature.com
Genetic polymorphism varies among species and within genomes, and has important
implications for the evolution and conservation of species. The determinants of this variation …

[HTML][HTML] Genetic diversity on the sex chromosomes

MAW Sayres - Genome biology and evolution, 2018 - ncbi.nlm.nih.gov
Levels and patterns of genetic diversity can provide insights into a population's history. In
species with sex chromosomes, differences between genomic regions with unique …

Extreme genomic erosion after recurrent demographic bottlenecks in the highly endangered Iberian lynx

F Abascal, A Corvelo, F Cruz, JL Villanueva-Cañas… - Genome biology, 2016 - Springer
Background Genomic studies of endangered species provide insights into their evolution
and demographic history, reveal patterns of genomic erosion that might limit their viability …

Human paternal and maternal demographic histories: insights from high-resolution Y chromosome and mtDNA sequences

S Lippold, H Xu, A Ko, M Li, G Renaud, A Butthof… - Investigative …, 2014 - Springer
Background Comparisons of maternally-inherited mitochondrial DNA (mtDNA) and
paternally-inherited non-recombining Y chromosome (NRY) variation have provided …

Incomplete lineage sorting rather than hybridization explains the inconsistent phylogeny of the wisent

K Wang, JA Lenstra, L Liu, Q Hu, T Ma, Q Qiu… - Communications …, 2018 - nature.com
The wisent or European bison is the largest European herbivore and is completely cross-
fertile with its American relative. However, mtDNA genome of wisent is similar to that of …

Deleterious variation shapes the genomic landscape of introgression

BY Kim, CD Huber, KE Lohmueller - PLoS Genetics, 2018 - journals.plos.org
While it is appreciated that population size changes can impact patterns of deleterious
variation in natural populations, less attention has been paid to how gene flow affects and is …

Accounting for eXentricities: analysis of the X chromosome in GWAS reveals X-linked genes implicated in autoimmune diseases

D Chang, F Gao, A Slavney, L Ma, YY Waldman… - PloS one, 2014 - journals.plos.org
Many complex human diseases are highly sexually dimorphic, suggesting a potential
contribution of the X chromosome to disease risk. However, the X chromosome has been …

XWAS: a software toolset for genetic data analysis and association studies of the X chromosome

F Gao, D Chang, A Biddanda, L Ma, Y Guo… - Journal of …, 2015 - academic.oup.com
XWAS is a new software suite for the analysis of the X chromosome in association studies
and similar genetic studies. The X chromosome plays an important role in human disease …

Indigenous Arabs are descendants of the earliest split from ancient Eurasian populations

JL Rodriguez-Flores, K Fakhro, F Agosto-Perez… - Genome …, 2016 - genome.cshlp.org
An open question in the history of human migration is the identity of the earliest Eurasian
populations that have left contemporary descendants. The Arabian Peninsula was the initial …

The fire ant social chromosome supergene variant Sb shows low diversity but high divergence from SB

R Pracana, A Priyam, I Levantis, RA Nichols… - Molecular …, 2017 - Wiley Online Library
Variation in social behaviour is common, yet little is known about the genetic architectures
underpinning its evolution. A rare exception is in the fire ant Solenopsis invicta: Alternative …