Human papillomavirus as a marker of the natural history and response to therapy of head and neck squamous cell carcinoma

KK Ang, EM Sturgis - Seminars in radiation oncology, 2012 - Elsevier
There has been a gradual change in the demographics of head and neck carcinoma.
Although relatively uncommon, the incidence of oropharyngeal carcinoma has been …

Human papillomavirus–associated oropharyngeal cancer: defining risk groups and clinical trials

A Bhatia, B Burtness - Journal of Clinical Oncology, 2015 - ascopubs.org
Human papillomavirus–associated oropharynx cancer (HPVA-OPC) is rapidly increasing in
incidence and has unique epidemiologic, molecular, and biologic characteristics. Despite …

Human papillomavirus testing in head and neck carcinomas: guideline from the College of American Pathologists

JS Lewis Jr, B Beadle, JA Bishop… - … of pathology & …, 2018 - meridian.allenpress.com
Context Human papillomavirus (HPV) is a major cause of oropharyngeal squamous cell
carcinomas, and HPV (and/or surrogate marker p16) status has emerged as a prognostic …

Atypical clinical behavior of p16-confirmed HPV-related oropharyngeal squamous cell carcinoma treated with radical radiotherapy

SH Huang, B Perez-Ordonez, FF Liu, J Waldron… - International Journal of …, 2012 - Elsevier
PURPOSE: To report atypical clinical behavior observed in human papillomavirus (HPV)–
related oropharyngeal carcinoma (OPC) treated with radiotherapy. METHODS AND …

The role of human papillomavirus in head and neck cancer

CB Lajer, CVON BUCHWALD - Apmis, 2010 - Wiley Online Library
Lajer CB, von Buchwald C. The role of human papillomavirus in head and neck cancer.
APMIS 2010; 118: 510–519. Over the last 20 years, there has been increasing awareness of …

AXL is a logical molecular target in head and neck squamous cell carcinoma

TM Brand, M Iida, AP Stein, KL Corrigan… - Clinical cancer …, 2015 - AACR
Purpose: Head and neck squamous cell carcinoma (HNSCC) represents the eighth most
common malignancy worldwide. Standard-of-care treatments for patients with HNSCC …

Activation of Wnt signaling pathway by human papillomavirus E6 and E7 oncogenes in HPV16-positive oropharyngeal squamous carcinoma cells

T Rampias, E Boutati, E Pectasides, C Sasaki… - Molecular Cancer …, 2010 - AACR
We sought to determine the role of human papillomavirus (HPV) E6 and E7 oncogenes in
nuclear β-catenin accumulation, a hallmark of activated canonical Wnt signaling pathway …

Current status of clinical testing for human papillomavirus in oropharyngeal squamous cell carcinoma

KY Kim, JS Lewis Jr, Z Chen - The Journal of Pathology …, 2018 - Wiley Online Library
While a variety of human papillomavirus (HPV) tests and surrogate markers are available,
currently there is no consensus on the best detection method (s) that should be used to …

Human papillomavirus predicts outcome in oropharyngeal cancer in patients treated primarily with surgery or radiation therapy

AM Hong, TA Dobbins, CS Lee, D Jones… - British journal of …, 2010 - nature.com
Objective: This study examines the prognostic significance of human papillomavirus (HPV)
in patients with locally advanced oropharyngeal squamous cell carcinoma (SCC) treated …

[HTML][HTML] Advances in the management of squamous cell carcinoma of the head and neck

JP Machiels, M Lambrecht, FX Hanin, T Duprez… - F1000prime …, 2014 - ncbi.nlm.nih.gov
Squamous cell carcinoma of the head and neck (SCCHN) is the sixth most common cancer
worldwide. The main risk factors for cancers of the oral cavity, larynx, oropharynx, and …