The main limitation in engineering in vitro tissues is the lack of a sufficient blood vessel
system—the vascularization. In vivo almost all tissues are supplied by these endothelial cell …

Endothelial progenitor cells (EPCs) have been isolated and shown to be effective in animal
models of ischemia, and many groups involved in clinical trials have demonstrated that EPC …

The cause of Alzheimer's disease (AD) is unknown. This gap in knowledge has created a
stumbling block in the search for a genuinely effective treatment or cure for this dementia …

Introduction Ischemic heart diseases, especially the myocardial infarction, is a major hazard
problem to human health. Despite substantial advances in control of risk factors and …

Over the years, cardiovascular diseases continue to increase and affect not only human
health but also the economic stability worldwide. The advancement in tissue engineering is …

Endothelial progenitor cells (EPCs) are recruited to ischemic regions and improve
neovascularization. Integrins contribute to EPC homing. High-mobility group box 1 (HMGB1) …

The mechanisms of homing of endothelial progenitor cells (EPCs) to sites of ischemia are
unclear. Here, we demonstrate that ex vivo–expanded EPCs as well as murine …

Abstract Background/Aims: Endothelial-to-mesenchymal transition (EndMT) plays significant
roles under various pathological conditions including cardiovascular diseases, fibrosis, and …

Angiogenesis represents the outgrowth of new blood vessels from existing ones, a
physiologic process that is vital to supply nourishment to newly forming tissues during …

Ischemic cardiovascular events are a major cause of death globally. Endothelial progenitor
cell (EPC)-based approaches can result in improvement of vascular perfusion and might …