The animal trypanosomiases and their chemotherapy: a review
Pathogenic animal trypanosomes affecting livestock have represented a major constraint to
agricultural development in Africa for centuries, and their negative economic impact is …
agricultural development in Africa for centuries, and their negative economic impact is …
A review of the antimalarial, antitrypanosomal, and antileishmanial activities of natural compounds isolated from Nigerian flora
The West African country Nigeria features highly diverse vegetation and climatic conditions
that range from rain forest bordering the Atlantic Ocean in the South to the Desert (Sahara) …
that range from rain forest bordering the Atlantic Ocean in the South to the Desert (Sahara) …
EuPathDB: the eukaryotic pathogen genomics database resource
C Aurrecoechea, A Barreto, EY Basenko… - Nucleic acids …, 2017 - academic.oup.com
Abstract The Eukaryotic Pathogen Genomics Database Resource (EuPathDB,
http://eupathdb. org) is a collection of databases covering 170+ eukaryotic pathogens …
http://eupathdb. org) is a collection of databases covering 170+ eukaryotic pathogens …
MetExplore: collaborative edition and exploration of metabolic networks
Metabolism of an organism is composed of hundreds to thousands of interconnected
biochemical reactions responding to environmental or genetic constraints. This metabolic …
biochemical reactions responding to environmental or genetic constraints. This metabolic …
Artificial intelligence guided discovery of a barrier-protective therapy in inflammatory bowel disease
Modeling human diseases as networks simplify complex multi-cellular processes, helps
understand patterns in noisy data that humans cannot find, and thereby improves precision …
understand patterns in noisy data that humans cannot find, and thereby improves precision …
EuPathDB: the eukaryotic pathogen genomics database resource
Fighting infections and developing novel drugs and vaccines requires advanced knowledge
of pathogen's biology. Readily accessible genomic, functional genomic, and population data …
of pathogen's biology. Readily accessible genomic, functional genomic, and population data …
The establishment of variant surface glycoprotein monoallelic expression revealed by single-cell RNA-seq of Trypanosoma brucei in the tsetse fly salivary glands
S Hutchinson, S Foulon, A Crouzols, R Menafra… - PLoS …, 2021 - journals.plos.org
The long and complex Trypanosoma brucei development in the tsetse fly vector culminates
when parasites gain mammalian infectivity in the salivary glands. A key step in this process …
when parasites gain mammalian infectivity in the salivary glands. A key step in this process …
Multi-label classification with XGBoost for metabolic pathway prediction
H Joe, HG Kim - BMC bioinformatics, 2024 - Springer
Background Metabolic pathway prediction is one possible approach to address the problem
in system biology of reconstructing an organism's metabolic network from its genome …
in system biology of reconstructing an organism's metabolic network from its genome …
Trypanosoma brucei: Metabolomics for analysis of cellular metabolism and drug discovery
F Fall, L Mamede, L Schioppa, A Ledoux, P De Tullio… - Metabolomics, 2022 - Springer
Background Trypanosoma brucei is the causative agent of Human African Trypanosomiasis
(also known as sleeping sickness), a disease causing serious neurological disorders and …
(also known as sleeping sickness), a disease causing serious neurological disorders and …
TriTrypDB: An integrated functional genomics resource for kinetoplastida
A Shanmugasundram, D Starns, U Böhme… - PLOS Neglected …, 2023 - journals.plos.org
Parasitic diseases caused by kinetoplastid parasites are a burden to public health
throughout tropical and subtropical regions of the world. TriTrypDB (https://tritrypdb. org) is a …
throughout tropical and subtropical regions of the world. TriTrypDB (https://tritrypdb. org) is a …