Obesity and cardiovascular disease: mechanistic insights and management strategies. A joint position paper by the World Heart Federation and World Obesity …

F Lopez-Jimenez, W Almahmeed… - European journal of …, 2022 - academic.oup.com
The ongoing obesity epidemic represents a global public health crisis that contributes to
poor health outcomes, reduced quality of life, and> 2.8 million deaths each year. Obesity is …

Prevalence of low-grade inflammation in depression: a systematic review and meta-analysis of CRP levels

EF Osimo, LJ Baxter, G Lewis, PB Jones… - Psychological …, 2019 - cambridge.org
BackgroundPeripheral low-grade inflammation in depression is increasingly seen as a
therapeutic target. We aimed to establish the prevalence of low-grade inflammation in …

Role of C-reactive protein at sites of inflammation and infection

NR Sproston, JJ Ashworth - Frontiers in immunology, 2018 - frontiersin.org
C-reactive protein (CRP) is an acute inflammatory protein that increases up to 1,000-fold at
sites of infection or inflammation. CRP is produced as a homopentameric protein, termed …

Risk assessment with gut microbiome and metabolite markers in NAFLD development

H Leung, X Long, Y Ni, L Qian, E Nychas… - Science translational …, 2022 - science.org
A growing body of evidence suggests interplay between the gut microbiota and the
pathogenesis of nonalcoholic fatty liver disease (NAFLD). However, the role of the gut …

Soluble urokinase plasminogen activator receptor (suPAR) as a biomarker of systemic chronic inflammation

LJH Rasmussen, JEV Petersen… - Frontiers in …, 2021 - frontiersin.org
Systemic chronic inflammation (SCI) is persistent, health-damaging, low-grade inflammation
that plays a major role in immunosenescence and in development and progression of many …

A guide to systematic review and meta-analysis of prognostic factor studies

RD Riley, KGM Moons, KIE Snell, J Ensor, L Hooft… - bmj, 2019 - bmj.com
Prognostic factors are associated with the risk of future health outcomes in individuals with a
particular health condition or some clinical start point (eg, a particular diagnosis). Research …

Atualização da diretriz brasileira de dislipidemias e prevenção da aterosclerose–2017

AA Faludi, MCO Izar, JFK Saraiva… - Arquivos brasileiros de …, 2017 - SciELO Brasil
Material de distribuição exclusiva à classe médica. Os Arquivos Brasileiros de Cardiologia
não se responsabilizam pelo acesso indevido a seu conteúdo e que contrarie a …

[HTML][HTML] Antiphospholipid antibodies in patients with COVID‐19: a relevant observation?

KMJ Devreese, EA Linskens, D Benoit… - Journal of Thrombosis …, 2020 - Elsevier
Background High incidence of thrombosis in COVID‐19 patients indicates a
hypercoagulable state. Hence, exploring the involvement of antiphospholipid antibodies …

[PDF][PDF] Obesity and inflammation: the linking mechanism and the complications

MS Ellulu, I Patimah, H Khaza'ai, A Rahmat… - Archives of medical …, 2017 - termedia.pl
Obesity is the accumulation of abnormal or excessive fat that may interfere with the
maintenance of an optimal state of health. The excess of macronutrients in the adipose …

The role of inflammation in depression: from evolutionary imperative to modern treatment target

AH Miller, CL Raison - Nature reviews immunology, 2016 - nature.com
Crosstalk between inflammatory pathways and neurocircuits in the brain can lead to
behavioural responses, such as avoidance and alarm, that are likely to have provided early …