In recent decades, mass spectrometry techniques, particularly when combined with
separation methods such as high-performance liquid chromatography, have become …

The consequences of matrix effects in mass spectrometry analysis are a major issue of
concern to analytical chemists. The identification of any ion suppressing (or enhancing) …

Matrix‐dependent signal suppression or enhancement represents a major drawback in
quantitative analysis with liquid chromatography coupled to atmospheric pressure ionization …

This is the part I of a tutorial review intending to give an overview of the state of the art of
method validation in liquid chromatography mass spectrometry (LC–MS) and discuss …

液相色谱-串联质谱技术作为强有力的分析工具已被广泛应用于多个领域,
但其检测中的基质效应对测定结果准确性的影响需引起重视. 本文综述了液相色谱 …

A novel rapid multiresidue/multiclass procedure with liquid chromatography tandem mass
spectrometry (LC–MS/MS) detection has been developed to screen for the presence of …

Selected reaction monitoring (SRM) performed on triple quadrupole mass spectrometers
has been the reference quantitative technique to analyze small molecules for several …

Non-targeted and suspect analyses with liquid chromatography/electrospray/high-resolution
mass spectrometry (LC/ESI/HRMS) are gaining importance as they enable identification of …

Lipids are ubiquitous in the human organism and play essential roles as components of cell
membranes and hormones, for energy storage or as mediators of cell signaling pathways …

Matrix effects caused by compounds endogenous to the biological sample are a primary
challenge in quantitative LC/MS/MS bioanalysis. Many approaches have been developed to …