Valproic acid (VPA) and its salts are psychotropic drugs that are widely used in neurological
diseases (epilepsy, neuropathic pain, migraine, etc.) and psychiatric disorders …

Valproic acid (VPA) induced rodent model of autism is a widely accepted and extensively
used rodent model to investigate the pharmacotherapy against autism. But, to date, its …

Pregnancy exposure of valproic acid (VPA) is widely adopted as a model of environmental
factor induced autism spectrum disorder (ASD). Increase of excitatory/inhibitory synaptic …

Synaptic alterations concomitant with neuroinflammation have been described in patients
and experimental models of autism spectrum disorder (ASD). However, the role of microglia …

Evidence suggests that long non-coding RNAs (lncRNAs) play a significant role in autism.
Herein, we explored the functional role and possible molecular mechanisms of NEAT1 in …

Autism spectrum disorder (ASD) is a complicated, interpersonally defined, static condition of
the underdeveloped brain. Although the aetiology of autism remains unclear, disturbance of …

Endoplasmic reticulum (ER) stress has been demonstrated to play important roles in a
variety of human diseases. However, their relevance to autism spectrum disorder (ASD) …

Background Extracellular nucleotides acting through specific purinergic receptors play a key
role in synaptic transmission and neuromodulation. Therefore, any deregulation of purine …

Humans are exposed to electromagnetic fields (EMF) from various sources throughout life.
Because humans are easily impacted by environmental factors during early development, it …

Background Evidence of an association between maternal use of anti-seizure medication
(ASM) during pregnancy and the risk of autism spectrum disorder (ASD) or attention …