Viral vectors have been used for a broad spectrum of gene therapy for both acute and
chronic diseases. In the context of cancer gene therapy, viral vectors expressing anti-tumor …

Oncolytic viruses are a new class of therapeutics which are largely in the experimental
stage, with just one virus approved by the FDA thus far. While the concept of oncolytic …

Current treatments for advanced hepatocellular carcinoma (HCC) have limited success in
improving patients' quality of life and prolonging life expectancy. The clinical need for more …

Simple Summary Peritoneal carcinomatosis is a challenging condition that affects many
cancer patients, and conventional therapies have limited efficacy in treating it. However …

Small extracellular vesicles (SEV) have attracted much attention both as mediators of
intercellular communication and as drug delivery systems. In addition, recent studies have …

Researchers have tried to find novel strategies for cancer treatment in the past decades.
Among the utilized methods, administering oncolytic viruses (OVs) alone or combined with …

The dominant cancer treatment modalities such as chemotherapy, radiotherapy, and even
targeted kinase inhibitors and mAbs are limited by low efficacy, toxicity, and treatment …

Alternative splicing (AS) is a central mechanism of genetic regulation which modifies the
sequence of RNA transcripts in higher eukaryotes. AS has been shown to increase both the …

Oncolytic viruses (OVs) are an emerging cancer therapeutic that are intended to act by
selectively targeting and lysing cancerous cells and by stimulating anti-tumour immune …

PEGylated liposomes (PEG-liposomes) are a promising drug delivery vehicle for tumor
targeting because of their efficient tumor disposition profiles via the enhanced permeability …