Epstein–Barr virus (EBV) is the first identified human oncogenic virus that can establish
asymptomatic life-long persistence. It is associated with a large spectrum of diseases …

Epstein-Barr virus (EBV) infects most people worldwide and persists for life due to
complicated interplay between lytic infection and multiple types of latent infections. While …

Hsp70s comprise a deeply conserved chaperone family that has a central role in
maintaining protein homeostasis. In humans, Hsp70 client specificity is provided by 49 …

SUMO modifications regulate the function of many proteins and are important in controlling
herpesvirus infections. We performed a site-specific proteomic analysis of SUMO1-and …

High-risk human papillomaviruses (HR-HPVs) promote cervical cancer as well as a subset
of anogenital and head and neck cancers. Due to their limited coding capacity, HPVs hijack …

Inhibition of host DNA damage response (DDR) is a common mechanism used by viruses to
manipulate host cellular machinery and orchestrate viral life cycles. Epstein-Barr virus …

Some lytic proteins encoded by Epstein-Barr virus (EBV) suppress host interferon (IFN)
signaling to facilitate viral replication. In this study, we sought to identify and characterize …

Many cellular processes pertinent for viral infection are regulated by the addition of small
ubiquitin-like modifiers (SUMO) to key regulatory proteins, making SUMOylation an …

Kaposi's sarcoma-associated herpesvirus (KSHV) protein ORF45 is a virion-associated
tegument protein that is unique to the gammaherpesvirus family. Generation of KSHV …

Simple Summary Epstein–Barr virus (EBV) is a gamma-herpesvirus associated with a broad
variety of cancers. It employs two modes of viral replication, ie, latent and lytic cycles in …