Kinetochores are large protein assemblies that connect chromosomes to microtubules of the
mitotic and meiotic spindles in order to distribute the replicated genome from a mother cell to …

In eukaryotes, chromosome segregation during cell division is facilitated by the kinetochore,
a multiprotein structure that is assembled on centromeric DNA. The kinetochore attaches …

Kinetochores are molecular machines that power chromosome segregation during the
mitotic and meiotic cell divisions of all eukaryotes. Aristotle explains how we think we have …

Chromosome segregation during mitosis requires assembly of the kinetochore complex at
the centromere. Kinetochore assembly depends on specific recognition of the histone …

Kinetochores are multisubunit complexes that assemble on centromeres to bind spindle
microtubules and promote faithful chromosome segregation during cell division. A 16 …

The propagation of all organisms depends on the accurate and orderly segregation of
chromosomes in mitosis and meiosis. Budding yeast has long served as an outstanding …

The kinetochore forms a dynamic interface with microtubules from the mitotic spindle during
mitosis. The Ndc80 complex acts as the key microtubule‐binding complex at kinetochores …

Centromeres direct the assembly of kinetochores, microtubule-attachment sites that allow
chromosome segregation on the mitotic spindle. Fundamental differences in size and …

Faithful chromosome segregation requires that sister chromatids establish bi-oriented
kinetochore-microtubule attachments. The spindle assembly checkpoint (SAC) prevents …

During mitosis, the spindle checkpoint senses kinetochores not properly attached to spindle
microtubules and prevents precocious sister-chromatid separation and aneuploidy. The …