The physiology of regulated BDNF release

T Brigadski, V Leßmann - Cell and Tissue Research, 2020 - Springer
The neurotrophic factor BDNF is an important regulator for the development of brain circuits,
for synaptic and neuronal network plasticity, as well as for neuroregeneration and …

Mechanisms controlling the expression and secretion of BDNF

JC Arévalo, R Deogracias - Biomolecules, 2023 - mdpi.com
Brain-derived nerve factor (BDNF), through TrkB receptor activation, is an important
modulator for many different physiological and pathological functions in the nervous system …

BDNF-trkB signaling in mitochondria: implications for neurodegenerative diseases

SK Soman, M Swain, RK Dagda - Molecular Neurobiology, 2024 - Springer
Brain-derived neurotrophic factor (BDNF) plays a pivotal role in neuronal development,
synaptic plasticity, and overall neuronal health by binding to its receptor, tyrosine receptor …

[HTML][HTML] Indole-3-carbinol and its derivatives as neuroprotective modulators

AA Singh, D Yadav, F Khan, M Song - Brain Sciences, 2024 - mdpi.com
Brain-derived neurotrophic factor (BDNF) and its downstream tropomyosin receptor kinase B
(TrkB) signaling pathway play pivotal roles in the resilience and action of antidepressant …

Biosensors, recent advances in determination of BDNF and NfL

A Mobed, S Charsouei, Y Yazdani, MK Gargari… - Cellular and Molecular …, 2023 - Springer
Key biomarkers such as Brain Derived Neurotrophic Factor (BDNF) and Neurofilament light
chain (NfL) play important roles in the development and progression of many neurological …

Synaptotagmin-4 induces anhedonic responses to chronic stress via BDNF signaling in the medial prefrontal cortex

J Kim, S Seol, TE Kim, J Lee, JW Koo… - Experimental & Molecular …, 2024 - nature.com
Stressful circumstances are significant contributors to mental illnesses such as major
depressive disorder. Anhedonia, defined as loss of the ability to enjoy pleasure in …

The BDNF Val66Met Polymorphism is a relevant, but not determinant, risk factor in the etiology of neuropsychiatric disorders–current advances in human studies: a …

GG de Assis, JR Hoffman - Brain Plasticity, 2022 - content.iospress.com
Brain-derived neurotrophic factor (BDNF) is the brain's most-produced neurotrophin during
the lifespan, essentially involved in multiple mechanisms of nervous system development …

Serum brain‐derived neurotrophic factor in coronary heart disease: Correlation with the T helper (Th) 1/Th2 ratio, Th17/regulatory T (Treg) ratio, and major adverse …

Y Huo, Q Feng, J Fan, J Huang, Y Zhu… - Journal of Clinical …, 2023 - Wiley Online Library
Background Brain‐derived neurotrophic factor (BDNF) exerts protective roles against
dyslipidemia, atherosclerosis, and inflammation in cardiovascular diseases; meanwhile, it …

Adenocarcinomas of the lung and neurotrophin system: a review

A Ricci, C Salvucci, S Castelli, A Carraturo, C de Vitis… - Biomedicines, 2022 - mdpi.com
Neurotrophins (NTs) represent a group of growth factors with pleiotropic activities at the
central nervous system level. The prototype of these molecules is represented by the nerve …

Visualization of reelin secretion from primary cultured neurons by bioluminescence imaging

Y Nakao, S Yokawa, T Kohno, T Suzuki… - The Journal of …, 2022 - academic.oup.com
Reelin is a secreted glycoprotein important for brain development and synaptic plasticity in
the adult brain. Some reports suggest that Reelin is secreted from the nerve terminals and …