[HTML][HTML] Drug uptake-based chemoresistance in breast cancer treatment

H Muley, R Fado, R Rodriguez-Rodriguez… - Biochemical …, 2020 - Elsevier
Breast cancer is the most prevalent type of tumor and the second leading cause of death
due to cancer among women. Although screening methods, diagnosis and therapeutic …

[HTML][HTML] Breast cancer: molecular mechanisms of underlying resistance and therapeutic approaches

M Tufail, J Cui, C Wu - American journal of cancer research, 2022 - ncbi.nlm.nih.gov
Breast cancer (BC) affects over 250,000 women in the US each year. Drug-resistant cancer
cells are responsible for most breast cancer fatalities. Scientists are developing novel …

The breast cancer stem cells traits and drug resistance

Q Zheng, M Zhang, F Zhou, L Zhang… - Frontiers in …, 2021 - frontiersin.org
Drug resistance is a major challenge in breast cancer (BC) treatment at present.
Accumulating studies indicate that breast cancer stem cells (BCSCs) are responsible for the …

Nanoparticles targeting receptors on breast cancer for efficient delivery of chemotherapeutics

S Jahan, ME Karim, EH Chowdhury - Biomedicines, 2021 - mdpi.com
The journey of chemotherapeutic drugs from the site of administration to the site of action is
confronted by several factors including low bioavailability, uneven distribution in major …

The role of breast cancer stem cells in chemoresistance and metastasis in triple-negative breast cancer

L He, N Wick, SK Germans, Y Peng - Cancers, 2021 - mdpi.com
Simple Summary Triple negative breast cancer lacks targeted therapies and has poor
prognosis; chemotherapy is currently the main treatment modality. Growing evidence has …

Titanium Carbide MXene Quantum Dots-Modified Hydroxyapatite Hollow Microspheres as pH/Near-Infrared Dual-Response Drug Carriers

M Liu, X Pan, Y Gan, M Gao, X Li, Z Liu, X Ma, M Geng… - Langmuir, 2023 - ACS Publications
Titanium carbide MXene quantum dots (MQDs) possess intrinsic regulatory properties and
selective toxicity to cancer cells. Here, MDQs were selected for the modification of …

Counteracting chemoresistance with metformin in breast cancers: targeting cancer stem cells

SM Samuel, E Varghese, L Koklesová, A Líšková… - Cancers, 2020 - mdpi.com
Despite the leaps and bounds in achieving success in the management and treatment of
breast cancers through surgery, chemotherapy, and radiotherapy, breast cancer remains the …

Oncogenic and stemness signatures of the high-risk HCMV strains in breast cancer progression

R El Baba, S Pasquereau, S Haidar Ahmad… - Cancers, 2022 - mdpi.com
Simple Summary Lately, human cytomegalovirus (HCMV) has been progressively
implicated in carcinogenesis alongside its oncomodulatory impact. CMV-Transformed …

Foliate-Targeting Quantum Dots-β-Cyclodextrin Nanocarrier for Efficient Delivery of Unsymmetrical Bisacridines to Lung and Prostate Cancer Cells

J Pilch, P Kowalik, A Kowalczyk, P Bujak… - International Journal of …, 2022 - mdpi.com
Targeted drug delivery by nanocarriers molecules can increase the efficiency of cancer
treatment. One of the targeting ligands is folic acid (FA), which has a high affinity for the folic …

FOXM1 mediates GDF-15 dependent stemness and intrinsic drug resistance in breast cancer

A Modi, P Purohit, D Roy, JR Vishnoi, P Pareek… - Molecular Biology …, 2022 - Springer
Background Stemness, a key component of breast cancer (BC) heterogeneity, is responsible
for chemoresistance. Growth differentiation factor-15 (GDF-15) induces drug resistance and …