Hyaluronic acid‐based Bioconjugate systems, Scaffolds, and their therapeutic potential

NG Kotla, IL Mohd Isa, A Larrañaga… - Advanced …, 2023 - Wiley Online Library
In recent years, the development of hyaluronic acid or hyaluronan (HA) based scaffolds,
medical devices, bioconjugate systems have expanded into a broad range of research and …

[HTML][HTML] Unlocking the mitochondria for nanomedicine-based treatments: overcoming biological barriers, improving designs, and selecting verification techniques

C Pegoraro, I Domingo-Ortí, I Conejos-Sánchez… - Advanced Drug Delivery …, 2024 - Elsevier
Enhanced targeting approaches will support the treatment of diseases associated with
dysfunctional mitochondria, which play critical roles in energy generation and cell survival …

Massively parallel pooled screening reveals genomic determinants of nanoparticle delivery

N Boehnke, JP Straehla, HC Safford, M Kocak… - Science, 2022 - science.org
To accelerate the translation of cancer nanomedicine, we used an integrated genomic
approach to improve our understanding of the cellular processes that govern nanoparticle …

Stiffness of targeted layer-by-layer nanoparticles impacts elimination half-life, tumor accumulation, and tumor penetration

SM Kong, DF Costa, A Jagielska… - Proceedings of the …, 2021 - National Acad Sciences
Nanoparticle (NP) stiffness has been shown to significantly impact circulation time and
biodistribution in anticancer drug delivery. In particular, the relationship between particle …

Polymeric nanoparticles-siRNA as an emerging nano-polyplexes against ovarian cancer

U Rehman, N Parveen, A Sheikh… - Colloids and Surfaces B …, 2022 - Elsevier
Ovarian cancer (OC) is considered fifth-deadliest cancer globally responsible for high
mortality in women. As the conventional therapeutic and diagnostic approaches are …

Polymer-modified liposomes for drug delivery: from fundamentals to applications

Y Cao, X Dong, X Chen - Pharmaceutics, 2022 - mdpi.com
Liposomes are highly advantageous platforms for drug delivery. To improve the colloidal
stability and avoid rapid uptake by the mononuclear phagocytic system of conventional …

Membrane engineering of cell membrane biomimetic nanoparticles for nanoscale therapeutics

M Zhang, S Cheng, Y Jin, N Zhang… - Clinical and …, 2021 - Wiley Online Library
In recent years, cell membrane camouflaging technology has emerged as an important
strategy of nanomedicine, and the modification on the membranes is also a promising …

Marine polysaccharides as a versatile biomass for the construction of nano drug delivery systems

Y Sun, X Ma, H Hu - Marine Drugs, 2021 - mdpi.com
Marine biomass is a treasure trove of materials. Marine polysaccharides have the
characteristics of biocompatibility, biodegradability, non-toxicity, low cost, and abundance …

Uniform Lithium Plating for Dendrite-Free Lithium Metal Batteries: Role of Dipolar Channels in Poly(vinylidene fluoride) and PbZrxTi1–xO3 Interface

BH Kang, SF Li, J Yang, ZM Li, YF Huang - ACS nano, 2023 - ACS Publications
Conventional polymer/ceramic composite solid-state electrolytes (CPEs) have limitations in
inhibiting lithium dendrite growth and fail to meet the contradictory requirements of anodes …

A user's guide to machine learning for polymeric biomaterials

TA Meyer, C Ramirez, MJ Tamasi, AJ Gormley - ACS Polymers Au, 2022 - ACS Publications
The development of novel biomaterials is a challenging process, complicated by a design
space with high dimensionality. Requirements for performance in the complex biological …