Visceral leishmaniasis (VL) is one of the major infectious diseases affecting the poorest
regions of the world. Current therapy is not very much satisfactory. The alarming rise of drug …

Post-kala-azar dermal leishmaniasis (PKDL) is a chronic, stigmatizing skin condition
occurring frequently after apparent clinical cure from visceral leishmaniasis. Given an urgent …

Background Glioma is a fatal tumor originating from the brain, which accounts for most
intracranial malignancies. Currently, Immunotherapy has turned into a novel and promising …

Leishmania infantum, the etiological agent of canine leishmaniosis (CanL) in Europe, was
responsible of the largest outbreak of human leishmaniosis in Spain. The parasite infects …

Macrophages are key innate immune cells in the tumor microenvironment that regulate
primary tumor growth, vascularization, metastatic spread and response to therapies …

Leishmaniasis is a neglected tropical disease affecting humans and domesticated animals
with high mortality in endemic countries. The pleiotropy of symptoms and the complicated …

The purpose of our work was to study the polymorphism of genes associated with disease
resistance and to search for their associations with productive traits in the population of the …

Despite advancements made toward diagnostics, tuberculosis caused by Mycobacterium
africanum (Maf) and Mycobacterium tuberculosis sensu stricto (Mtbss) remains a major …

Kidney renal clear cell carcinoma (KIRC) is a highly immune-infiltrated kidney cancer with
the highest mortality rate and the greatest potential for invasion and metastasis. Solute …

Background Fucosidosis is an autosomal recessive lysosomal storage disease caused by
defective alpha-l-fucosidase (FUCA1) activity, leading to the accumulation of fucose …