Molecular imaging in gastroenterology
R Atreya, M Goetz - Nature Reviews Gastroenterology & Hepatology, 2013 - nature.com
Molecular imaging is a novel field in gastroenterology that uses fluorescently labelled
probes to specifically highlight neoplastic lesions on the basis of their molecular signature …
probes to specifically highlight neoplastic lesions on the basis of their molecular signature …
Detection of sessile serrated adenomas in the proximal colon using wide-field fluorescence endoscopy
Background & Aims Many cancers in the proximal colon develop via from sessile serrated
adenomas (SSAs), which have flat, subtle features that are difficult to detect with …
adenomas (SSAs), which have flat, subtle features that are difficult to detect with …
Molecular endoscopic imaging in cancer
S Ahmed, S Strand, J Weinmann‐Menke… - Digestive …, 2018 - Wiley Online Library
Cancer is one of the major causes of death in both the USA and Europe. Molecular imaging
is a novel field that is revolutionizing cancer management. It is based on the molecular …
is a novel field that is revolutionizing cancer management. It is based on the molecular …
Design and synthesis of near-infrared peptide for in vivo molecular imaging of HER2
We report the development, characterization, and validation of a peptide specific for the
extracellular domain of HER2. This probe chemistry was developed for molecular imaging …
extracellular domain of HER2. This probe chemistry was developed for molecular imaging …
EGFR overexpressed in colonic neoplasia can be detected on wide-field endoscopic imaging
OBJECTIVES: Colorectal cancer initially lies dormant as dysplasia, a premalignant state that
provides an opportunity for early cancer detection. Dysplasia can be flat in morphology, focal …
provides an opportunity for early cancer detection. Dysplasia can be flat in morphology, focal …
[HTML][HTML] Overexpressed claudin-1 can be visualized endoscopically in colonic adenomas in vivo
Background & Aims Conventional white-light colonoscopy aims to reduce the incidence and
mortality of colorectal cancer (CRC). CRC has been found to arise from missed polypoid and …
mortality of colorectal cancer (CRC). CRC has been found to arise from missed polypoid and …
Endoscopy-guided orthotopic implantation of colorectal cancer cells results in metastatic colorectal cancer in mice
D Bettenworth, MM Mücke, K Schwegmann… - Clinical & experimental …, 2016 - Springer
Advanced stage colorectal cancer (CRC) is still associated with limited prognosis. For
preclinical evaluation of novel therapeutic approaches, murine models with orthotopic tumor …
preclinical evaluation of novel therapeutic approaches, murine models with orthotopic tumor …
Detection of early murine colorectal cancer by MMP-2/-9–guided fluorescence endoscopy
K Schwegmann, D Bettenworth… - Inflammatory bowel …, 2016 - academic.oup.com
Background Patients with ulcerative colitis are at increased risk for colorectal cancer and
endoscopic surveillance is mandatory. Matrix metalloproteinases (MMPs)-2 and-9 activities …
endoscopic surveillance is mandatory. Matrix metalloproteinases (MMPs)-2 and-9 activities …
Membrane Bound Peroxiredoxin-1 Serves as a Biomarker for In Vivo Detection of Sessile Serrated Adenomas
Aim: Sessile serrated adenomas (SSAs) are premalignant lesions driven by the BRAFV600E
mutation to give rise to colorectal cancers (CRCs). They are often missed during white light …
mutation to give rise to colorectal cancers (CRCs). They are often missed during white light …
[HTML][HTML] Advanced gastrointestinal endoscopic imaging for inflammatory bowel diseases
GE Tontini, T Rath, H Neumann - World Journal of …, 2016 - ncbi.nlm.nih.gov
Gastrointestinal luminal endoscopy is of paramount importance for diagnosis, monitoring
and dysplasia surveillance in patients with both, Crohn's disease and ulcerative colitis …
and dysplasia surveillance in patients with both, Crohn's disease and ulcerative colitis …