Adult hippocampal neurogenesis, fear generalization, and stress
The generalization of fear is an adaptive, behavioral, and physiological response to the
likelihood of threat in the environment. In contrast, the overgeneralization of fear, a cardinal …
likelihood of threat in the environment. In contrast, the overgeneralization of fear, a cardinal …
Single-cell activity and network properties of dorsal raphe nucleus serotonin neurons during emotionally salient behaviors
The serotonin system modulates a wide variety of emotional behaviors and states, including
reward processing, anxiety, and social interaction. To reveal the underlying patterns of …
reward processing, anxiety, and social interaction. To reveal the underlying patterns of …
Post-traumatic stress disorder: the relationship between the fear response and chronic stress
Post-traumatic stress disorder (PTSD) is a disabling psychiatric condition that can develop
following a physical, psychological, or sexual trauma. Despite the growing body of literature …
following a physical, psychological, or sexual trauma. Despite the growing body of literature …
Amygdala-hippocampal dynamics during salient information processing
Recognizing motivationally salient information is critical to guiding behaviour. The amygdala
and hippocampus are thought to support this operation, but the circuit-level mechanism of …
and hippocampus are thought to support this operation, but the circuit-level mechanism of …
Dorsolateral septum somatostatin interneurons gate mobility to calibrate context-specific behavioral fear responses
A Besnard, Y Gao, M TaeWoo Kim, H Twarkowski… - Nature …, 2019 - nature.com
Adaptive fear responses to external threats rely upon efficient relay of computations
underlying contextual encoding to subcortical circuits. Brain-wide analysis of highly …
underlying contextual encoding to subcortical circuits. Brain-wide analysis of highly …
Intracranial human recordings reveal association between neural activity and perceived intensity for the pain of others in the insula
Based on neuroimaging data, the insula is considered important for people to empathize
with the pain of others. Here, we present intracranial electroencephalographic (iEEG) …
with the pain of others. Here, we present intracranial electroencephalographic (iEEG) …
Prediction of learned resistance or helplessness by hippocampal-prefrontal cortical network activity during stress
DB Marques, RN Ruggiero… - Journal of …, 2022 - Soc Neuroscience
The perception of control over a stressful experience may determine its impacts and
generate resistance against future stressors. Although the medial prefrontal cortex (PFC) …
generate resistance against future stressors. Although the medial prefrontal cortex (PFC) …
Endocannabinoid release at ventral hippocampal-amygdala synapses regulates stress-induced behavioral adaptation
The endocannabinoid (eCB) system is a key modulator of glutamate release within limbic
neurocircuitry and thus heavily modulates stress responsivity and adaptation. The ventral …
neurocircuitry and thus heavily modulates stress responsivity and adaptation. The ventral …
Fear extinction recall modulates human frontomedial theta and amygdala activity
Human functional magnetic resonance imaging (fMRI) and electroencephalography (EEG)
studies, as well as animal studies, indicate that the amygdala and frontomedial brain regions …
studies, as well as animal studies, indicate that the amygdala and frontomedial brain regions …
Basolateral amygdala inputs to the medial entorhinal cortex selectively modulate the consolidation of spatial and contextual learning
Although evidence suggests that the basolateral amygdala (BLA) and dorsal hippocampus
(DH) work together to influence the consolidation of spatial/contextual learning, the circuit …
(DH) work together to influence the consolidation of spatial/contextual learning, the circuit …