Systemic arterial hypertension and heart failure are cardiovascular diseases that affect
millions of individuals worldwide. They are characterized by a change in the autonomic …

Preeclampsia (PE) is characterized by hypertension, autonomic imbalance and
inflammation. The subfornical organ (SFO) reportedly relays peripheral inflammatory …

The goal of our study was to analyze the time course of the effect of NG-nitro-L-arginine
methyl ester (L-NAME) on nitric oxide synthase (NOS) isoforms and nuclear factor–κB (NF …

Objective: Preeclampsia is a hypertensive disorder of pregnancy marked by an excessive
inflammatory response. The anti-inflammatory effect of pyridostigmine (PYR) was previously …

Background Autonomic nervous dysfunction is a shared clinical feature in Alzheimer's
disease (AD) and heart failure (HF). Cholinesterase inhibitors (ChEIs) are widely used …

Exposure to polycyclic aromatic hydrocarbons (PAHs) may cause neurobehavioral changes.
This study aimed to explore the underlying mechanism of PAH neurotoxicity in coal miners …

Homocysteine (Hcy) is an independent cardiovascular disease (CVD) risk factor, whose
mechanisms are poorly understood. We aimed to explore mild hyperhomocysteinemia …

With the alarming rise in cases of arterial hypertension worldwide, there is an urgent need to
develop combined therapies to mitigate this scenario. Rose oxide (RO), a monoterpene with …

Cisplatin treatment induces an autonomic dysfunction and gastrointestinal and
cardiovascular disorders. Physical exercise as well as pyridostigmine treatment induces …

Abstract β-Adrenergic blockers are no longer recommended as first-line therapy due to the
reduced cardioprotection of traditional β-blockers compared with other antihypertensive …