Host–microbiota interactions are fundamental for the development of the immune system.
Drastic changes in modern environments and lifestyles have led to an imbalance of this …

Metabolites produced by the host and microbiota play a crucial role in how human bodies
develop and remain healthy. Most of these metabolites are produced by microbiota and …

Multisystem inflammatory syndrome in children (MIS-C) manifests as a severe and
uncontrolled inflammatory response with multiorgan involvement, occurring weeks after …

Despite multiple associations between the microbiota and immune diseases, their role in
autoimmunity is poorly understood. We found that translocation of a gut pathobiont …

Efforts to understand autoimmunity have been pursued relentlessly for several decades. It
has become apparent that the immune system evolved multiple mechanisms for controlling …

Although there is little direct evidence supporting that stress affects cancer incidence, it does
influence the evolution, dissemination and therapeutic outcomes of neoplasia, as shown in …

Anticancer immune responses can be considered a desirable form of autoimmunity that may
be profoundly shaped by the microbiome. Here, we discuss evidence for the microbiome's …

Western lifestyle is linked to autoimmune and metabolic diseases, driven by changes in diet
and gut microbiota composition. Using Toll-like receptor 7 (TLR7)-dependent mouse models …

Objective Prevotella copri, an intestinal microbe, may overexpand in stool samples from
patients with new‐onset rheumatoid arthritis (RA), but it is not yet clear whether the organism …

The earliest autoantibodies in lupus are directed against the RNA binding autoantigen
Ro60, but the triggers against this evolutionarily conserved antigen remain elusive. We …