Plasmodium vivax threatens nearly half the world's population and is a significant
impediment to achievement of the millennium development goals. It is an important, but …

Absent or severely diminished activity of ADAMTS13 (A Disintegrin And Metalloprotease
with a ThromboSpondin type 1 motif, member 13) resulting in the intravascular persistence …

It is not known why people are more susceptible to bacterial infections such as nontyphoid
Salmonella during and after a malaria infection, but in mice, malarial hemolysis impairs …

Anemia is a common complication of malaria that is characterized by the loss of infected and
uninfected erythrocytes. In mouse malaria models, clearance of uninfected erythrocytes is …

We have investigated the impact of persistent intravascular hemolysis on liver dysfunction
using the mouse malaria model. Intravascular hemolysis showed a positive correlation with …

Severe anemia is a major cause of death by malaria. The loss of uninfected erythrocytes is
an important contributor to malarial anemia; however, the mechanisms underlying this …

Background Transcriptomic research of blood cell lineages supports the understanding of
distinct features of the immunopathology in human malaria. Methods We used microarray …

Severe anemia is an important contributor to mortality in children with severe malaria.
Anemia in malaria is a multi-factorial complication, since dyserythropoiesis, hemolysis and …

The human spleen is an immune sentinel and controls red blood cell (RBC) quality. By
mechanically retaining subsets of infected RBCs, the spleen may reduce the pace at which …

Semi-immunity against Pf malaria is based on a combination of cellular and humoral
immune responses. PMNs and IgGs are considered important components of this process …