Rabies control and treatment: from prophylaxis to strategies with curative potential

S Zhu, C Guo - Viruses, 2016 - mdpi.com
Rabies is an acute, fatal, neurological disease that affects almost all kinds of mammals.
Vaccination (using an inactivated rabies vaccine), combined with administration of rabies …

Rabies vaccines: where do we stand, where are we heading?

M Kaur, R Garg, S Singh, R Bhatnagar - Expert review of vaccines, 2015 - Taylor & Francis
Rabies being the most lethal zoonotic, vaccine-preventable viral disease with worldwide
distribution of reservoir wild animals presents unique challenges for its diagnosis …

The Combination of Molecular Adjuvant CCL35.2 and DNA Vaccine Significantly Enhances the Immune Protection of Carassius auratus gibelio against CyHV-2 …

X Huo, C Fan, T Ai, J Su - Vaccines, 2020 - mdpi.com
Cyprinid herpesvirus 2 (CyHV-2) infection results in huge economic losses in gibel carp
(Carassius auratus gibelio) industry. In this study, we first constructed recombinant plasmids …

The effects of CCL3, CCL4, CCL19 and CCL21 as molecular adjuvants on the immune response to VAA DNA vaccine in flounder (Paralichthys olivaceus)

H Xu, J Xing, X Tang, X Sheng, W Zhan - Developmental & Comparative …, 2020 - Elsevier
The magnitude of the immune response induced by DNA vaccines depends on the amount
and type of antigen-presenting cells attracted to the injection site. In our previous study, a …

Cholera toxin B subunit acts as a potent systemic adjuvant for HIV-1 DNA vaccination intramuscularly in mice

J Hou, Y Liu, J Hsi, H Wang, R Tao… - Human vaccines & …, 2014 - Taylor & Francis
Cholera toxin B subunit (CTB) was investigated as a classical mucosal adjuvant that can
increase vaccine immunogenicity. In this study, we found out the in vitro efficacy of cholera …

Molecular adjuvant HMGB1 enhances anti-influenza immunity during DNA vaccination

P Fagone, DJ Shedlock, H Bao, OU Kawalekar, J Yan… - Gene therapy, 2011 - nature.com
DNA-based vaccines, while highly immunogenic in mice, generate significantly weaker
responses in primates. Therefore, current efforts are aimed at increasing their …

Postexposure treatment with the live-attenuated rabies virus (RV) vaccine TriGAS triggers the clearance of wild-type RV from the Central Nervous System (CNS) …

J Li, A Ertel, C Portocarrero, DA Barkhouse… - Journal of …, 2012 - Am Soc Microbiol
Postexposure treatment (PET) of wild-type rabies virus (RV)-infected mice with a live-
attenuated triple-glycoprotein RV variant (TriGAS) promotes survival but does not prevent …

[HTML][HTML] Advances in rabies prophylaxis and treatment with emphasis on immunoresponse mechanisms

A El-Sayed - International journal of veterinary science and …, 2018 - Elsevier
Rabies is a vaccine-preventable fatal disease in man and most mammals. Although rabies is
recorded in 150 territories and is responsible for at least 60,000 human deaths every year …

Co‐immunization with an optimized plasmid‐encoded immune stimulatory interleukin, high‐mobility group box 1 protein, results in enhanced interferon‐γ secretion by …

G Muthumani, DJ Laddy, SG Sundaram… - …, 2009 - Wiley Online Library
DNA vaccination is a novel immunization strategy that has great potential for the
development of vaccines and immune therapeutics. This strategy has been highly effective …

Mixed vector immunization with recombinant adenovirus and MVA can improve vaccine efficacy while decreasing antivector immunity

A Reyes-Sandoval, CS Rollier, A Milicic, K Bauza… - Molecular therapy, 2012 - cell.com
Substantial protection can be provided against the pre-erythrocytic stages of malaria by
vaccination first with an adenoviral and then with an modified vaccinia virus Ankara (MVA) …