Current and emerging topical antibacterials and antiseptics: agents, action, and resistance patterns

DA Williamson, GP Carter… - Clinical microbiology …, 2017 - Am Soc Microbiol
Bacterial skin infections represent some of the most common infectious diseases globally.
Prevention and treatment of skin infections can involve application of a topical antimicrobial …

Modes of action of three disinfectant active substances: a review

S Wessels, H Ingmer - Regulatory toxicology and pharmacology, 2013 - Elsevier
This review deals with three categories of active substances for disinfectant products, their
modes of action (MOA), and how MOA can help predict propensity for resistance in …

Review and phylogenetic analysis of qac genes that reduce susceptibility to quaternary ammonium compounds in Staphylococcus …

T Wassenaar, D Ussery, L Nielsen… - European Journal of …, 2015 - akjournals.com
The qac genes of Staphylococcus species encode multidrug efflux pumps: membrane
proteins that export toxic molecules and thus increase tolerance to a variety of compounds …

Has resistance to chlorhexidine increased among clinically-relevant bacteria? A systematic review of time course and subpopulation data

S Buxser - PLoS One, 2021 - journals.plos.org
Chlorhexidine (CHX) was introduced for use as an antimicrobial more than 70 years ago.
CHX has been and continues to be used broadly for disinfecting surfaces in medical and …

Increasing usage of chlorhexidine in health care settings: blessing or curse? A narrative review of the risk of chlorhexidine resistance and the implications for infection …

B Van den Poel, V Saegeman… - European Journal of …, 2022 - Springer
Chlorhexidine digluconate (CHG) is an antiseptic frequently used in hospitals to prevent
healthcare-related infections. It is used in different formulations for skin antisepsis, oral care …

Staphylococcus capitis: insights into epidemiology, virulence, and antimicrobial resistance of a clinically relevant bacterial species

DM Crepin, M Chavignon, PO Verhoeven… - Clinical Microbiology …, 2024 - journals.asm.org
Staphylococcus capitis is divided into two subspecies, S. capitis subsp. ureolyticus
(renamed urealyticus in 1992; ATCC 49326) and S. capitis subsp. capitis (ATCC 27840) …

Characterization of pre-antibiotic era Klebsiella pneumoniae isolates with respect to antibiotic/disinfectant susceptibility and virulence in Galleria mellonella

ME Wand, KS Baker, G Benthall… - Antimicrobial agents …, 2015 - Am Soc Microbiol
The EGD Murray collection consists of approximately 500 clinical bacterial isolates, mainly
Enterobacteriaceae, isolated from around the world between 1917 and 1949. A number of …

Susceptibility of vancomycin-resistant and -sensitive Enterococcus faecium obtained from Danish hospitals to benzalkonium chloride, chlorhexidine and hydrogen …

SMI Alotaibi, A Ayibiekea… - Journal of Medical …, 2017 - microbiologyresearch.org
Purpose. In Danish hospitals, the number of infections caused by vancomycin-resistant
Enterococcus faecium (VRE faecium) has dramatically increased in recent years. Hospital …

Synthesis, crystal structure, and biological activity of a multidentate calix [4] arene ligand doubly functionalized by 2-hydroxybenzeledene-thiosemicarbazone

E Bahojb Noruzi, B Shaabani, S Geremia, N Hickey… - Molecules, 2020 - mdpi.com
The design and synthesis of a novel tert-butyl-calix [4] arene functionalized at 1, 3 positions
of the lower rim with two terminal 2-hydroxybenzeledene-thiosemicarbazone moieties is …

Bacterial sensitivity to chlorhexidine and povidone-iodine antiseptics over time: A systematic review and meta-analysis of human-derived data

R Aftab, VH Dodhia, C Jeanes, RG Wade - Scientific Reports, 2023 - nature.com
Surgical site infection (SSI) is the most common complication of surgery, increasing
healthcare costs and hospital stay. Chlorhexidine (CHX) and povidone-iodine (PVI) are …