Bone is the most implanted tissue after blood. The major solid components of human bone
are collagen (a natural polymer, also found in skin and tendons) and a substituted …

Hydroxyapatite, the main inorganic material in natural bone, has been used widely for
orthopaedic applications. Due to size effects and surface phenomena at the nanoscale …

An osteochondral scaffold has a chondrogenic spiral scaffold in one end of an outer shell
made of sintered microspheres, and an osteogenic spiral scaffold in the other end of the …

Compounds that had neither calcined nor sintered hydroxyapatite (u-HA) particles
(particulate size 0.2–20μm, averaging 3.0 μm, Ca/P= 1.69, and containing CO2-3) uniformly …

Two dicalcium phosphate dihydrate (DCPD) hydraulic cements and one apatite hydraulic
cement were implanted in epiphyseal and metaphyseal, cylindrical bone defects of sheep …

Fabricating functionally graded scaffolds from biodegradable polymers to enable the
mimicking of native tissue is an important challenge. Here we demonstrate the fabrication …

Calcium phosphate based bioceramics have been widely used for orthopedic applications
due to their chemical similarity to natural bone. The Ca/P stoichiometry of calcium …

Natural bone growth greatly depends on the precedent vascular network that supplies
oxygen and essential nutrients and removes metabolites. Likewise, it is crucial for tissue …

Research using animal models provides important knowledge of pathological conditions
that even tually can lead to the development of more effective clinical treatment of diseases …

Human mesenchymal stem cells (hMSCs) have great potential in bone tissue engineering,
and hydroxyapatite (HA), a natural component of human hard tissues, is believed to support …