Personalized hydrogels for engineering diverse fully autologous tissue implants

R Edri, I Gal, N Noor, T Harel, S Fleischer… - Advanced …, 2019 - Wiley Online Library
Despite incremental improvements in the field of tissue engineering, no technology is
currently available for producing completely autologous implants where both the cells and …

Thymosin beta 4: a potential novel therapy for neurotrophic keratopathy, dry eye, and ocular surface diseases

G Sosne, D Rimmer, HK Kleinman, G Ousler - Vitamins and hormones, 2016 - Elsevier
Chronic ocular surface diseases such as dry eye, blepharitis, and neurotrophic
keratopathies represent a significant and a growing therapeutic challenge. The basis of this …

Thymosin β4 and the vasculature: multiple roles in development, repair and protection against disease

KN Dubé, N Smart - Expert opinion on biological therapy, 2018 - Taylor & Francis
Introduction: Formation of the vasculature is a complex process, defects in which can lead to
embryonic lethality or disease in later life. Understanding mechanisms of vasculogenesis …

Injectable cardiac cell microdroplets for tissue regeneration

I Gal, R Edri, N Noor, M Rotenberg, M Namestnikov… - Small, 2020 - Wiley Online Library
One of the strategies for heart regeneration includes cell delivery to the defected heart.
However, most of the injected cells do not form quick cell–cell or cell–matrix interactions …

Upk3b Is Dispensable for Development and Integrity of Urothelium and Mesothelium

C Rudat, T Grieskamp, C Röhr, R Airik, C Wrede… - PloS one, 2014 - journals.plos.org
The mesothelium, the lining of the coelomic cavities, and the urothelium, the inner lining of
the urinary drainage system, are highly specialized epithelia that protect the underlying …

Transcriptional profiling reveals ductus arteriosus-specific genes that regulate vascular tone

EL Shelton, G Ector, CL Galindo… - Physiological …, 2014 - journals.physiology.org
Failure of the ductus arteriosus (DA) to close at birth can lead to serious complications.
Conversely, certain profound congenital cardiac malformations require the DA to be patent …

Optimizing the biofabrication process of omentum-based scaffolds for engineering autologous tissues

N Soffer-Tsur, M Shevach, A Shapira, D Peer… - Biofabrication, 2014 - iopscience.iop.org
Omentum-based matrices fabricated by decellularization have the potential to serve as
autologous scaffolds for tissue engineering. Transplantation of such scaffolds prepared from …

Identification of a novel developmental mechanism in the generation of mesothelia

NI Winters, RT Thomason, DM Bader - Development, 2012 - journals.biologists.com
Mesothelium is the surface layer of all coelomic organs and is crucial for the generation of
their vasculature. Still, our understanding of the genesis of this essential cell type is …

ECM-based macroporous sponges release essential factors to support the growth of hematopoietic cells

N Soffer-Tsur, D Peer, T Dvir - Journal of Controlled Release, 2017 - Elsevier
The success of hematopoietic stem cells (HSCs) transplantation is limited due to the low
number of HSCs received from donors. In vivo, HSCs reside within a specialized niche …

Bone tissue engineering in the greater omentum is enhanced by a periosteal transplant in a miniature pig model

H Naujokat, M Lipp, Y Açil, H Wieker… - Regenerative …, 2019 - Taylor & Francis
Aim: Reconstruction of bone defects with autologous grafts has certain disadvantages. The
aim of this study is to introduce a new type of living bioreactor for engineering of bone flaps …