Impaired brain glucose metabolism is considered a hallmark of brain dysfunction and
neurodegeneration. Disruption of the hexosamine biosynthetic pathway (HBP) and …

The development of central nervous system (CNS) can form perceptual, memory, and
cognitive functions, while injuries to CNS often lead to severe neurological dysfunction and …

The precise development of neuronal morphologies is crucial to the establishment of
synaptic circuits and, ultimately, proper brain function. Signaling by the axon guidance cue …

The neurofilament (NF) cytoskeleton is critical for neuronal morphology and function. In
particular, the neurofilament-light (NF-L) subunit is required for NF assembly in vivo and is …

The O-GlcNAcylation is a ubiquitous, nutrient-sensing, and reversible post-translational
modification of nucleocytoplasmic and mitochondrial proteins. It is a unique glucose rheostat …