Quinoxalinones are a class of heterocyclic compounds which attract extensive attention
owing to their potential in the field of organic synthesis and medicinal chemistry. During the …

Tryptamine, a tryptophan-derived monoamine similar to 5-hydroxytryptamine (5-HT), is
produced by gut bacteria and is abundant in human and rodent feces. However, the …

This review article covers the recent developments in direct C–H functionalization of
quinoxalin-2 (1H)-one derivatives via radical additions at the C3 position. Reaction types …

A visible light-mediated direct C–H arylation of quinoxalin-2 (1H)-ones with aryl acyl
peroxides has been developed. The reaction proceeds smoothly through a radical process …

A method of synthesizing 3-arylquinoxalin-2 (1 H)-ones using diaryliodonium
tetrafluoroborates under mild conditions is described. This protocol has a wide substrate …

A photoredox-catalyzed direct arylation of quinoxalin-2-(1 H)-ones using diaryliodonium
triflates as the convenient, stable, and cheap aryl source is described. A broad variety of …

A transition metal‐free direct C‐3 arylation of quinoxalin‐2 (1H)‐ones with arylamines has
been explored. This reaction proceeded smoothly through a radical process under mild …

Cholera is a global health problem with no targeted therapies. The Ca2+-sensing receptor
(CaSR) is a regulator of intestinal ion transport and a therapeutic target for diarrhea, and …

A simple and practical visible-light-induced protocol has been developed for the
construction of 3-arylquinoxa-lin-2 (1H)-ones via Eosin Y-catalyzed direct CH 3-arylation of …

Available CFTR modulators provide no therapeutic benefit for cystic fibrosis (CF) caused by
many loss-of-function mutations in the cystic fibrosis transmembrane conductance regulator …