Investigation on the molecular interaction between dietary flavone luteolin and alpha-2-macroglobulin using multi-spectroscopic, calorimetric and molecular dynamics …
The current study examined the mechanism of interaction between luteolin and human
αlpha-2-macroglobulin (α2M) to determine the binding mode and the interaction of the …
αlpha-2-macroglobulin (α2M) to determine the binding mode and the interaction of the …
Insight into the molecular interaction between the anticancer drug, enzalutamide and human alpha-2-macroglobulin: Biochemical and biophysical approach
The drug pharmacokinetics is affected upon binding with proteins, thus making drug-protein
interactions crucial. This study investigated the interaction between enzalutamide and …
interactions crucial. This study investigated the interaction between enzalutamide and …
Synthesis and Characterization of Silver Nanoparticles (AgNPs) using Chemico-physical Methods
Silver nanoparticles (AgNPs) have several applications in nanoscience and nanomedicine
such as antibacterial, antifungal, anti-inflammatory and anti-angiogenic properties. In the …
such as antibacterial, antifungal, anti-inflammatory and anti-angiogenic properties. In the …
In vitro anticancer effects in hepatocellular carcinoma (HCC) and protein interaction study of xanthoangelol
Q Li, Z Lou, C Wang, Y Li - International Journal of Biological …, 2024 - Elsevier
Abstract Xanthoangelol (C 25 H 28 O 4), a natural flavonoid derived from chalcones, has
shown potential pharmacological activities. However, its primary interaction mechanism with …
shown potential pharmacological activities. However, its primary interaction mechanism with …
Elucidating the Binding Interaction of a Highly Efficient Phytochemical-Sinapic Acid with Human Serum Albumin: A Spectroscopic and Calorimetric Approach
Polyphenolic compounds have received much attention due to their major function as
antioxidants. Sinapic acid (SA) is an orally bioavailable phytochemical with excellent free …
antioxidants. Sinapic acid (SA) is an orally bioavailable phytochemical with excellent free …
[HTML][HTML] Biological evaluation of sophoridine by interaction with plasma transport protein and protective effects in cardiomyocytes
Z Wu, S Cheng, S Wang, W Li, J Liu - Arabian Journal of Chemistry, 2024 - Elsevier
Numerous studies have demonstrated the protective benefits of sophoridine, a bioactive
alkaloid, on cell damage. However, its primary biological properties such as interaction with …
alkaloid, on cell damage. However, its primary biological properties such as interaction with …
Phycocyanobilin is a new binding partner of human alpha-2-macroglobulin that protects the protein against oxidative stress
Under simulated physiological conditions, this study investigates the interaction between
nutraceutical phycocyanobilin (PCB) and the universal anti-protease protein human alpha-2 …
nutraceutical phycocyanobilin (PCB) and the universal anti-protease protein human alpha-2 …
Interaction of silver nanoparticles with human alpha-2-macroglobulin: Biochemical and Biophysical Investigation
Background: Silver nanoparticles (AgNPs) have a broad spectrum of applications in
nanoscience and nanomedicine due to their flexible properties, such as antibacterial …
nanoscience and nanomedicine due to their flexible properties, such as antibacterial …
Characterization of the binding between anti-tumor drug 5-fluorouracil and human alpha-2-macroglobulin: spectroscopic and molecular docking analyses
MK Zia, T Siddiqui, H Ahsan… - Journal of Biomolecular …, 2022 - Taylor & Francis
Fluorouracil (5-FU) is a well-recognized anticancer drug used in the treatment of tumors of
head, neck and breast. Drug pharmacokinetics is affected upon binding with protein, thus …
head, neck and breast. Drug pharmacokinetics is affected upon binding with protein, thus …
A single protein to multiple peptides: Investigation of protein-peptide relationship using targeted alpha-2-macroglobulin analysis
Recent advances in proteomics technologies have enabled analysis of thousands of
proteins in a high-throughput manner. Mass Spectrometry (MS) based proteomics, uses a …
proteins in a high-throughput manner. Mass Spectrometry (MS) based proteomics, uses a …