1, 2, 3-Triazole-containing hybrids as potential anticancer agents: Current developments, action mechanisms and structure-activity relationships

Z Xu, SJ Zhao, Y Liu - European journal of medicinal chemistry, 2019 - Elsevier
Anticancer agents are critical for the cancer treatment, but side effects and the drug
resistance associated with the currently used anticancer agents create an urgent need to …

Click chemistry in natural product modification

X Zhang, S Zhang, S Zhao, X Wang, B Liu… - Frontiers in Chemistry, 2021 - frontiersin.org
Click chemistry is perhaps the most powerful synthetic toolbox that can efficiently access the
molecular diversity and unique functions of complex natural products up to now. It enables …

Understanding the interfacial science of nature-inspired materials for versatile applications

GD Kumar, RM Rego, HJ Rao, NR Nadar, S Kabiri… - Surfaces and …, 2024 - Elsevier
Recently, nature-inspired materials have received substantial attention in the scientific
community due to their intriguing characteristics, such as the ability to tailor or mimic stimuli …

Design and synthesis of parthenolide and 5-fluorouracil conjugates as potential anticancer agents against drug resistant hepatocellular carcinoma

Y Ding, S Li, W Ge, Z Liu, X Zhang, M Wang… - European Journal of …, 2019 - Elsevier
A series of twenty-three parthenolide-5-fluorouracil (5-FU) conjugates ware synthesized and
evaluated for their anti-cancer activities against human hepatocellular carcinoma cell line …

The current and potential therapeutic uses of parthenolide

S Agatonovic-Kustrin, DW Morton - Studies in natural products chemistry, 2018 - Elsevier
Many plants containing terpenoids are used in traditional medicine for their pain-relieving
and antiinflammatory properties. A well-known example is parthenolide, a sesquiterpene …

Five Himalayan weeds as potential bioresources for bioactive agents: toxic compounds to valuable scaffolds

E Bala, V Aggarwal, P Kumar, R Sharma, Saima… - Phytochemistry …, 2024 - Springer
Natural products are highly prevalent in Himalayan region clustered in medicinal and
aromatic plants including weeds. Toxic weed plants are of serious concerns due to their …

[PDF][PDF] Synthesis, antioxidant activity and molecular docking study of 1, 2, 4-Triazole and their corresponding fused rings containing 2-Methylphenol

RM Shakir, SA Saoud, HS Jasim… - International Journal of …, 2021 - researchgate.net
ABSTRACT Newly 4-amino-1, 2, 4-triazole-3-thione ring 2 was formed at position six of 2-
methylphenol from the reaction of 6-(5-thio-1, 3, 4-oxadiazol-2-yl)-2-methylphenol 1 with …

Bioactivities and the structural modification of Parthenolide: a review

J Wu, X Wang, Y Hou, P Gong - Medicinal Chemistry Research, 2024 - Springer
Parthenolide, a sesquiterpene lactone derived from Feverfew (Tanacetum parthenium)
buds, has attracted significant attention due to its versatile pharmacological potential. It and …

Synthesis of novel spiro-pyrazole and spiro-isoxazoline derivatives of 9α-and 9β-hydroxyparthenolide

F Outahar, M Moumou, A Hannioui, EM Rakib… - Tetrahedron …, 2020 - Elsevier
A series of novel spiropyrazoles and spiroisoxazolines was efficiently synthesized. Structural
modifications were performed at the C-9 and C-13 positions of 9α-and 9β …

Synthesis of Novel Propynyl Monoterpene Analogues and their Conjugates with β-DGlucopyranosides

RR Gubaidullin, YA Perfilova… - Current Organic …, 2024 - ingentaconnect.com
Camphor and carvone exhibit a broad spectrum of biological activity, which determines the
prospect of their use as a platform for functionalization to obtain the analogues as potential …