[HTML][HTML] mRNA vaccines for COVID-19: what, why and how

JW Park, PNP Lagniton, Y Liu… - International journal of …, 2021 - ncbi.nlm.nih.gov
Abstract The Coronavirus disease-19 (COVID-19) pandemic, caused by severe acute
respiratory syndrome coronavirus-2 (SARS-CoV-2), has impacted human lives in the most …

RIG-I and other RNA sensors in antiviral immunity

KT Chow, M Gale Jr, YM Loo - Annual review of immunology, 2018 - annualreviews.org
Pattern recognition receptors (PRRs) survey intra-and extracellular spaces for pathogen-
associated molecular patterns (PAMPs) within microbial products of infection. Recognition …

Regulation of long non-coding RNAs and genome dynamics by the RNA surveillance machinery

L Nair, H Chung, U Basu - Nature reviews Molecular cell biology, 2020 - nature.com
Much of the mammalian genome is transcribed, generating long non-coding RNAs
(lncRNAs) that can undergo post-transcriptional surveillance whereby only a subset of the …

The intricate balance between microRNA‐induced mRNA decay and translational repression

P Naeli, T Winter, AP Hackett, L Alboushi… - The FEBS …, 2023 - Wiley Online Library
Post‐transcriptional regulation of messenger RNAs (mRNAs)(ie, mechanisms that control
translation, stability and localization) is a critical focal point in spatiotemporal regulation of …

IGF2BP3 promotes mRNA degradation through internal m7G modification

C Liu, X Dou, Y Zhao, L Zhang, L Zhang, Q Dai… - Nature …, 2024 - nature.com
Recent studies have suggested that mRNA internal m7G and its writer protein METTL1 are
closely related to cell metabolism and cancer regulation. Here, we identify that IGF2BP …

[图书][B] Genomes 5

TA Brown - 2023 - taylorfrancis.com
Genomes 5 has been completely revised and updated. It is a thoroughly modern textbook
about genomes and how they are investigated. As with previous Genomes editions …

Post-transcriptional regulation of gene expression and human disease

AH Corbett - Current opinion in cell biology, 2018 - Elsevier
A large number of mutations in genes that encode RNA binding proteins cause human
disease. Many of these RNA binding proteins mediate key steps in post-transcriptional …

RNA-binding proteins control gene expression and cell fate in the immune system

M Turner, MD Díaz-Muñoz - Nature immunology, 2018 - nature.com
RNA-binding proteins (RBPs) are essential for the development and function of the immune
system. They interact dynamically with RNA to control its biogenesis and turnover by …

The Integrator complex cleaves nascent mRNAs to attenuate transcription

DC Tatomer, ND Elrod, D Liang, MS Xiao… - Genes & …, 2019 - genesdev.cshlp.org
Cellular homeostasis requires transcriptional outputs to be coordinated, and many events
post-transcription initiation can dictate the levels and functions of mature transcripts. To …

[PDF][PDF] A hMTR4‐PDIA3P1‐miR‐125/124‐TRAF6 regulatory axis and its function in NF kappa B signaling and chemoresistance

C Xie, LZ Zhang, ZL Chen, WJ Zhong, JH Fang… - …, 2020 - Wiley Online Library
Background and Aims DNA damage‐induced NF‐κB activation is a major obstacle to
effective antitumour chemotherapy. Long noncoding RNAs (lncRNAs) that regulate …