The role of Staphylococcus aureus enterotoxin B in chronic rhinosinusitis with nasal polyposis

Z Chegini, M Didehdar, A Khoshbayan… - Cell Communication and …, 2022 - Springer
CRS with nasal polyps (CRSwNP) is a multifactorial disease, and various etiological factors
like bacterial superantigens are known to develop this disease. Recent studies reported that …

[PDF][PDF] Immune cell responses and mucosal barrier disruptions in chronic rhinosinusitis

R Khalmuratova, JW Park, HW Shin - Immune network, 2017 - synapse.koreamed.org
Chronic rhinosinusitis (CRS) is one of the most common presentations of upper airway
illness and severely affects patient quality of life. Its frequency is not surprising given levels …

[HTML][HTML] DEP-induced ZEB2 promotes nasal polyp formation via epithelial-to-mesenchymal transition

M Lee, S Lim, YS Kim, R Khalmuratova, SH Shin… - Journal of Allergy and …, 2022 - Elsevier
Background Diesel exhaust particles (DEPs) are associated with the prevalence and
exacerbation of allergic respiratory diseases, including allergic rhinitis and allergic asthma …

Type 2/Th2‐driven inflammation impairs olfactory sensory neurogenesis in mouse chronic rhinosinusitis model

A Rouyar, M Classe, R Gorski, MD Bock, J Le‐Guern… - Allergy, 2019 - Wiley Online Library
Background Chronic rhinosinusitis (CRS) with nasal polyps (CRS w NP) is a chronic
inflammatory disease often accompanied by impairment of sense of smell. This symptom …

Innate immunity and chronic rhinosinusitis: what we have learned from animal models

NR London Jr, AP Lane - Laryngoscope investigative …, 2016 - Wiley Online Library
Objective Chronic rhinosinusitis (CRS) is a heterogeneous and multifactorial disease
characterized by dysregulated inflammation. Abnormalities in innate immune function …

[HTML][HTML] Host-microbe interactions in chronic rhinosinusitis biofilms and models for investigation

EJ Vanderpool, KP Rumbaugh - Biofilm, 2023 - Elsevier
Chronic rhinosinusitis (CRS) is a debilitating condition characterized by long-lasting
inflammation of the paranasal sinuses. It affects a significant portion of the population …

Aeroallergens, air pollutants, and chronic rhinitis and rhinosinusitis

NR London Jr, I Lina… - World journal of …, 2018 - mednexus.org
Chronic rhinitis and rhinosinusitis are among the most common conditions world-wide with
significant morbidity and decreased quality of life. Although the pathogenesis of these …

Models for the study of nasal and sinus physiology in health and disease: A review of the literature

AA Al‐Sayed, RU Agu… - Laryngoscope investigative …, 2017 - Wiley Online Library
Objective Chronic sinusitis is a very common yet poorly understood medical condition with
significant morbidity. Hence, it remains an entity that is difficult to treat with unsatisfactory …

Lipopolysaccharide-initiated rhinosinusitis causes neuroinflammation and olfactory dysfunction in mice

CF Yeh, WH Huang, MY Lan… - American Journal of …, 2023 - journals.sagepub.com
Background Olfactory dysfunction is a common disease and it may be caused by sinonasal
inflammation, toxin inhalation, or neurological disorders. After sinonasal inflammation, if both …

STAT6 Blockade Abrogates Aspergillus-Induced Eosinophilic Chronic Rhinosinusitis and Asthma, A Model of Unified Airway Disease

H Sun, A Damania, ML Mair, E Otukoya, YD Li… - Frontiers in …, 2022 - frontiersin.org
Unified airway disease, including concurrent asthma and chronic rhinosinusitis (CRS), is a
common, but poorly understood disorder with no curative treatment options. To establish a …